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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & NanoFolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) NanoFolder
MCC 0.627 > 0.316
Average MCC ± 95% Confidence Intervals 0.574 ± 0.443 > 0.345 ± 0.403
Sensitivity 0.507 > 0.324
Positive Predictive Value 0.781 > 0.316
Total TP 75 > 48
Total TN 24522 > 24466
Total FP 32 < 114
Total FP CONTRA 0 < 15
Total FP INCONS 21 < 89
Total FP COMP 11 > 10
Total FN 73 < 100
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 75
Total TN 24522
Total FP 32
Total FP CONTRA 0
Total FP INCONS 21
Total FP COMP 11
Total FN 73
Total Scores
MCC 0.627
Average MCC ± 95% Confidence Intervals 0.574 ± 0.443
Sensitivity 0.507
Positive Predictive Value 0.781
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 48
Total TN 24466
Total FP 114
Total FP CONTRA 15
Total FP INCONS 89
Total FP COMP 10
Total FN 100
Total Scores
MCC 0.316
Average MCC ± 95% Confidence Intervals 0.345 ± 0.403
Sensitivity 0.324
Positive Predictive Value 0.316
Nr of predictions 4

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.48 0.46 0.51 25 7091 24 2 22 0 29
4A1C_2 0.00 0.00 0.00 0 11728 61 12 41 8 33
4AOB_A 0.33 0.29 0.39 12 4340 20 1 18 1 30
4ENC_A 0.57 0.58 0.58 11 1307 9 0 8 1 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.