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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Carnac(seed)
MCC 0.802 > 0.000
Average MCC ± 95% Confidence Intervals 0.803 ± 0.061 > 0.000 ± 0.000
Sensitivity 0.779 > 0.000
Positive Predictive Value 0.827 > 0.000
Total TP 1031 > 0
Total TN 736828 < 738075
Total FP 375 > 0
Total FP CONTRA 21 > 0
Total FP INCONS 195 > 0
Total FP COMP 159 > 0
Total FN 293 < 1324
P-value 2.00627773251e-08

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Performance plots


  1. Comparison of performance of MXScarna(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 1031
Total TN 736828
Total FP 375
Total FP CONTRA 21
Total FP INCONS 195
Total FP COMP 159
Total FN 293
Total Scores
MCC 0.802
Average MCC ± 95% Confidence Intervals 0.803 ± 0.061
Sensitivity 0.779
Positive Predictive Value 0.827
Nr of predictions 13

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.55 0.52 0.58 58 101375 62 5 37 20 53
RFA_00601 0.81 0.80 0.81 91 99123 42 5 16 21 23
RFA_00602 0.72 0.72 0.73 83 101361 51 6 25 20 33
SRP_00011 0.78 0.75 0.81 78 46264 28 0 18 10 26
SRP_00015 0.91 0.88 0.95 87 46268 20 0 5 15 12
SRP_00152 0.88 0.85 0.91 88 45656 20 1 8 11 15
SRP_00178 0.89 0.86 0.92 88 45657 16 0 8 8 14
SRP_00179 0.91 0.88 0.95 92 45959 17 0 5 12 13
SRP_00181 0.83 0.81 0.84 83 45957 24 0 16 8 19
SRP_00182 0.88 0.86 0.90 87 45959 19 0 10 9 14
SRP_00184 0.81 0.79 0.82 79 45960 27 0 17 10 21
SRP_00188 0.74 0.67 0.83 53 31061 16 1 10 5 26
SRP_00308 0.73 0.73 0.74 64 36228 33 3 20 10 24

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 738075
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1324
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 13

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116
SRP_00011 0.00 0.00 0.00 0 46360 0 0 0 0 104
SRP_00015 0.00 0.00 0.00 0 46360 0 0 0 0 99
SRP_00152 0.00 0.00 0.00 0 45753 0 0 0 0 103
SRP_00178 0.00 0.00 0.00 0 45753 0 0 0 0 102
SRP_00179 0.00 0.00 0.00 0 46056 0 0 0 0 105
SRP_00181 0.00 0.00 0.00 0 46056 0 0 0 0 102
SRP_00182 0.00 0.00 0.00 0 46056 0 0 0 0 101
SRP_00184 0.00 0.00 0.00 0 46056 0 0 0 0 100
SRP_00188 0.00 0.00 0.00 0 31125 0 0 0 0 79
SRP_00308 0.00 0.00 0.00 0 36315 0 0 0 0 88

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.