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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & NanoFolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) NanoFolder
MCC 0.876 > 0.144
Average MCC ± 95% Confidence Intervals 0.876 ± 0.056 > 0.145 ± 1.950
Sensitivity 0.788 > 0.173
Positive Predictive Value 0.976 > 0.134
Total TP 41 > 9
Total TN 5764 > 5739
Total FP 3 < 59
Total FP CONTRA 1 < 6
Total FP INCONS 0 < 52
Total FP COMP 2 > 1
Total FN 11 < 43
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and NanoFolder).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 41
Total TN 5764
Total FP 3
Total FP CONTRA 1
Total FP INCONS 0
Total FP COMP 2
Total FN 11
Total Scores
MCC 0.876
Average MCC ± 95% Confidence Intervals 0.876 ± 0.056
Sensitivity 0.788
Positive Predictive Value 0.976
Nr of predictions 2

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.88 0.78 1.00 21 2464 2 0 0 2 6

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 9
Total TN 5739
Total FP 59
Total FP CONTRA 6
Total FP INCONS 52
Total FP COMP 1
Total FN 43
Total Scores
MCC 0.144
Average MCC ± 95% Confidence Intervals 0.145 ± 1.950
Sensitivity 0.173
Positive Predictive Value 0.134
Nr of predictions 2

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00571 -0.01 0.00 0.00 0 3286 36 6 29 1 25
PDB_00828 0.30 0.33 0.28 9 2453 23 0 23 0 18

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.