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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Carnac(seed)
MCC 0.695 > 0.000
Average MCC ± 95% Confidence Intervals 0.692 ± 0.323 > 0.000 ± 0.000
Sensitivity 0.680 > 0.000
Positive Predictive Value 0.712 > 0.000
Total TP 232 > 0
Total TN 301859 < 302185
Total FP 155 > 0
Total FP CONTRA 16 > 0
Total FP INCONS 78 > 0
Total FP COMP 61 > 0
Total FN 109 < 341
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 232
Total TN 301859
Total FP 155
Total FP CONTRA 16
Total FP INCONS 78
Total FP COMP 61
Total FN 109
Total Scores
MCC 0.695
Average MCC ± 95% Confidence Intervals 0.692 ± 0.323
Sensitivity 0.680
Positive Predictive Value 0.712
Nr of predictions 3

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.55 0.52 0.58 58 101375 62 5 37 20 53
RFA_00601 0.81 0.80 0.81 91 99123 42 5 16 21 23
RFA_00602 0.72 0.72 0.73 83 101361 51 6 25 20 33

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 302185
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 341
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.