Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric Murlet(20) MXScarna(20)
MCC 0.621 > 0.589
Average MCC ± 95% Confidence Intervals 0.620 ± 0.161 > 0.595 ± 0.103
Sensitivity 0.544 > 0.534
Positive Predictive Value 0.708 > 0.650
Total TP 2368 > 2323
Total TN 12465477 > 12465249
Total FP 1159 < 1652
Total FP CONTRA 149 < 185
Total FP INCONS 828 < 1065
Total FP COMP 182 < 402
Total FN 1981 < 2026
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Murlet(20) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and MXScarna(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(20) and MXScarna(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and MXScarna(20)).

^top





Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 2368
Total TN 12465477
Total FP 1159
Total FP CONTRA 149
Total FP INCONS 828
Total FP COMP 182
Total FN 1981
Total Scores
MCC 0.621
Average MCC ± 95% Confidence Intervals 0.620 ± 0.161
Sensitivity 0.544
Positive Predictive Value 0.708
Nr of predictions 9

^top



2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00177 0.75 0.70 0.81 330 1178473 93 14 63 16 143
CRW_00250 0.75 0.68 0.84 325 1198537 73 14 50 9 153
CRW_00278 0.75 0.67 0.83 302 1129893 75 12 49 14 148
CRW_00280 0.78 0.72 0.85 328 1117874 75 11 47 17 125
CRW_00330 0.39 0.31 0.49 160 1988690 189 26 139 24 357
CRW_00411 0.31 0.25 0.40 122 1615195 206 23 163 20 374
CRW_00414 0.33 0.29 0.36 146 1665818 288 38 223 27 349
CRW_00789 0.78 0.71 0.86 318 1137416 79 8 44 27 129
PDB_01105 0.73 0.62 0.86 337 1433581 81 3 50 28 203

^top



Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 2323
Total TN 12465249
Total FP 1652
Total FP CONTRA 185
Total FP INCONS 1065
Total FP COMP 402
Total FN 2026
Total Scores
MCC 0.589
Average MCC ± 95% Confidence Intervals 0.595 ± 0.103
Sensitivity 0.534
Positive Predictive Value 0.650
Nr of predictions 9

^top



2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00177 0.62 0.56 0.68 264 1178492 152 16 108 28 209
CRW_00250 0.73 0.67 0.79 321 1198521 119 12 72 35 157
CRW_00278 0.71 0.62 0.80 280 1129906 107 12 58 37 170
CRW_00280 0.72 0.66 0.78 301 1117875 125 10 74 41 152
CRW_00330 0.41 0.37 0.45 190 1988597 294 32 196 66 327
CRW_00411 0.49 0.46 0.52 227 1615066 271 42 168 61 269
CRW_00414 0.39 0.37 0.41 181 1665782 316 50 212 54 314
CRW_00789 0.67 0.60 0.75 268 1137427 134 8 83 43 179
PDB_01105 0.64 0.54 0.75 291 1433583 134 3 94 37 249

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.