RNA is one of the most important molecules in almost all life processes. Its catalytic powers and biological importance have made this molecule an important subject of scientific research. Our aim is to provide an innovative product in the form of an engineered enzyme - a ribonuclease (eRNase) that possesses the ability to cleave dsRNA within desired sequence specific place. This unique prototype product can be used in a broad spectrum of applications in biotechnology, pharma and related fields. Thanks to multidisciplinary approach within our project we built up the knowledge and methods to commercialize this invention in a number of practical applications.