Results for job: PAPD1_HUMAB_iso_1
All residues whose disorder probability is over 0.5 are considered as disordered.For visibility only 4 plots corresponding to predictions from final metapredictions had been shown. To see results from primary methods click on the shadowed name of method in legend (the left side of plot).
Alternatively you can see results in simple text format here
Short description of meta methods:
MetaDisorderMD2 -CASP9 winning method
(group number 147) - a method based on 13 disorder predictors and gaps
in alignment produced by 8 fold recognition methods, optimized by Sww
score (see Help page for details) using genetic algorithm. If you are looking for the most
accurate disorder predictor, you should use this one, according CASP9
its AUC is 0.839; MetaDisorderMD2 result file 
MetaDisorderMD - (group 374, fourth place in CASP9), AUC 0.816, similar to MetaDisorderMD2, but during optimization via AUC is 0.839; MetaDisorderMD result file
MetaDisorder - CASP8 winning method (group 153 in casp8, and group 010 in casp9) - metaprediction based on 13 disorder predictors AUC is 0.839; MetaDisorder3D result file
MetaDisorder3D - (group 421), counts gaps as disorder in top ten alignments produced by 8 different fold recognition methods, method and alignment efficiency to detect disorder was optimized by GA, tested during CASP9 as a reference to other meta methods, results are far AUC is 0.839; MetaDisorder result file
MetaDisorderMD - (group 374, fourth place in CASP9), AUC 0.816, similar to MetaDisorderMD2, but during optimization via AUC is 0.839; MetaDisorderMD result file
MetaDisorder - CASP8 winning method (group 153 in casp8, and group 010 in casp9) - metaprediction based on 13 disorder predictors AUC is 0.839; MetaDisorder3D result file
MetaDisorder3D - (group 421), counts gaps as disorder in top ten alignments produced by 8 different fold recognition methods, method and alignment efficiency to detect disorder was optimized by GA, tested during CASP9 as a reference to other meta methods, results are far AUC is 0.839; MetaDisorder result file
Primary predictors used by meta methods:
a) fold recognition methods:
HHsearch run over pdb70 database
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 2ikf A | 100.00 |  |
-------------------------------------------------------------------------------------------------------------------------------MGSSHHHHHHSSGLVPRGS---------------------HMPPSP----------AVVGRSLVNSFKQFVSKDLHTRHVDATYRLVLDCVAAVDPLMRLYTFGSTVYGVHEKGSDVDFVVLNKTDVEDGKG------------GDAATQKGLQADILAKLARVIRQK-HLSWNVEEVRRTRVPVVRVKG-GGAVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRHLQFVPPSTIDVS--------RVEPLPP-HL---PLEEPADEGLELGTQVLDFLHFFLEFDSDKQVISLNRPGITTKEEKYQWCIEDPYELNLNVGRNVTPLKRDFLRRHLEKARDTALLTIV-------------------------------------------------------------------- | |
| 3hj4 A | 100.00 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAKREFIRGMMAHYRASLPPPEHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISLTYRNFSPWLQ----------------GMERVDEQNNKRMFGKEAS--AMGMEDV-RYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILCAIRQFPDFYGAYIHLVKAWGKAREVIAPE-RSTFNSFTVTTMALMVLQEL--GLLPVFSKPTG---EFGELTVADAEMLLQE--FKLPLHDDDEKLGEALQRFAEYYAKYDFSAGTVSLIHPRRHREWEKSPYVVED-FVNYVNCGRRVQASRVRHIQQEFNRLREMLIDKESEL---------KFDEVFRESDTVP-------------------------------------------- | |
| 3nyb A | 100.00 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------GSYPWILHDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELGGK------------------------ESRNNLYSLASHLKKK-NLATEVEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHT-GGLGGFSIICLVFSFLHMH-PRIITN-------------------------EI------DPKDNLGVLLIEFFELYGNFGYDDVALGSSDGYPFPKSTPFSLAIQDPGDESNNISRG--SFNIRDIKKAFAGAFDLLTNRCFELHSATDRLGKSILGNVIKY------------------------------------------------ | |
| 2b4v A | 100.00 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------SPLSLPSTKLNPSPDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMVYGQMERGSDLDLACMFDDPYPSHEVQAKRTNLLGLTEARTPVEKVAARTALLYIAEKMGRFFPDGKIMTRGMREDYDVLRFVPEMFMYRWDISFV-GYGVKNSYLIRHYLHNGPVARHTAMAVKAWGKATNVGAGS-GAMLTSYAVTVMFIYYLLVTDPWSLPHPAHLPRY-------------PDFS-P----LYDCDPTELGRLLHGFFIFYAHFDYEREVVSLNRNRRSYRSDIGNFCIEDPYEDGLNLVRHLHPAKFQLVKQEFLRAAQCMERFL---PTNAPE--KSILGV-KR------------ADLRHFERDRD-------RE----------------- | |
| 2hhp A | 100.00 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQKVFGITGPVSTVGAT--AAENKLNDSLIQELKKSFETEQETANRVQVLKILQELAQRFVSGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVT-------------------------REDFFTVFDSLLRE-RKELDEIAPVPDAFVPIIKIKF--SGISIDLICARLNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIF-GFPGGVAWAMLVARICQLY-----PN------------------------------------ACSAVILNRFFIILSEWNWPQ-PVILKPGPQVRVWNSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFS------NKKSWA--NLFEKNDFFFSDEQHLKWSGLVESKVRLLVMKLEVLFTKPFESSYGSHKVTDEN | |
| 1q79 A | 100.00 | |
---------------------------------------------------------------------------------------------------------------------------------------------MPFPVTTQ----GSQQTQP-PQKHYGITSPISLAAPK--ETDALLTQKLVETLKPVFEEEEELQRRILILGKLNNLVKEWIVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVD-------------------------RSDFFTSFYDKLKL-QEEVKDLRAVEEAFVPVIKLCF--DGIEIDILFARLAGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNIL-GFLGGVSWAMLVARTCQLY-----PN------------------------------------AIASTLVHKFFLVFSKWEWPNPVLQPEECNLLPVWDYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLS------KAEWS--KLFEAPNFFQKEKQRLEWVGLVESKIRILVGSLEKNEPQSFPAPKETYDIQSFT | |
| 1px5 A | 99.14 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEL------RHTPARDLDKFIDHLLPNTXFRTQVKEAIDIVXRFLKERFRVSKVVKGGSSGKGTTLRGSDADLVVFLTKLTSFEDQL------------------RRRGEFIQEIRRQLEACQREQFKVTEVQSPENPSFVLSSPQQEVEFDVLAFDALGQWPNPLIKEFRNRPTKLKSLIRLVKHWYQTCKKTH--GNKLPPQYALELLTVYAWEQGSR--------------KTDFSTAQG----F-------------QTVLELVLKHLCFWEYYDFTNPVVGRCMLQQL---KKPRPVILDPADPTGNVGGG-DTHSWQRLAQEARVW---LGYPCCKNLDGSLVGAWTMLQKI--------------------------------------------------- | |
| 1r89 A | 98.68 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDE-LG-VEYVFVGSYARNTWLKGLEIDVFLLFPEEFSKEELRE---------------------RGLEIGKAVLDSY--------EIRYAEHPYVHGVVK--GVEVDVPKNIKSAFHHKWLE---GRIKG-KENEVRLLKGFLKANGIYGAYKVRGFSGYLCELLIVFYGSFLE-----TVKNA---RRWTRRTV-------------------------------------IDVA-------KG---EVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREF---MEAPSL-----GFFKPKRVFAVKFRK-PDIVDDNLYPQLERASRKIFEFLER------------ENFMPLRSFC | |
| 1fjc A | 97.27 | |
-----------------------------------------------------------SHMLEDPCTSKKVRAARTLLAKNSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAEKNLEE---KQGAEIDG-----RSVSLYYTGEKGGTRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ |
HHsearch run over CDD database
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| COG5260 | 100.00 | |
---------------------------------------------------------------------------------------------------------MNRSSKLFI--------------SLNSSSEEEFETIMEQKERR-PL--------DAKKVSIQELLELS-IDSVFNEESDELTSELLEFYDYIAPSDEELKRRKALLEKLRTLLKKEFPDADLKVFGSTETGLALPKSDIDLCIISDPRGYKET----------------------RNAG-SLASHLFKK--NLAKEVVVVSTARVPIIKLVDPQSGLHCDISFNNTNGIVNAKLIRSYLKEDPRLRPLVLIIKHWLKRRALNDVA-TGTLSSYTISCMVLSFLQMHPPF---LF-------------FDNG-------LLSPLKYNKNIDNLGVLFDDFFELYGSFNYSLVVLSINSGFYLPKYEKGWLSIQDPG-TDRNNDISAVSFNIKDIKAAFIRAFELLSNKLFTLTSAIKHDAYGLLIEFN---EASYSNTS-RS-------LKEEYDSIYEKAPYNKVDPYVLDEISSQY | |
| d2b4va1 | 100.00 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVAARHTAMAVKAWGKATNVGAGSG-AMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHLP-----RYPDF-------SPLYDCDPTELGRLLHGFFIFYAHFDYEREVVSLNRNRRSYRSDIYNFCIEDPYEGGLNLVRHLHPAKFQLVKQEFLRAAQCMERFLPT------NAPESILG----------------------------------------------------- | |
| pfam0492 | 100.00 | |
-------------------------------------------------------------------------------------------------------------------------------------------------TKQY-----------------GVTKPISTAGPT--PADLELSEELIKFLKEEFESEEETKKREEVLEKLNKIVKEWAAGGKIFTFGSYRLGVHGPGSDIDTLCVAPRHVT-------------------------REDFFSSFYEILKGR-PEVTELHPVEDAFVPIIKFKF--DGISIDLLFASLADLLDDSLLRNLDENKEVFRTALRCIKLWAKRRGIYSNVL-GFLGGVAWAILVARVCQLY-----P-----------------------------------N-ASPSTLVSKFFRIFSQWQWPNPVLKPIEGRLNPSDRYHLMPIITPAYPSMNSTHNVTRSTLKVITEELKRGNEITKEILL------GKAPWSD--LFE-------------------------------------------------- | |
| lcl|cons | 100.00 | |
---------------------------------------------------------------------------------------------------------MAES-----------QDFLPVSPSSSDSPSFGSLPSEPIEAEKWMIAEER---TKE----------IHCHSSPSNLVSERLRNEILDFVQYLIPTPEEIEVRSELVEKIRDVVKQKWPDASVYVFGSVPTGLYLPDSDIDLVVLSKFLNDKEDR-----------------------AVKLELALELEE-DNSAFHVKVVQKARVPIIKFKDPVSNIHVDISFNQTNGVKAAKFIKDFLRDHPFLRSLVLVLKQFLYERRLNGVH-TGGISSYALELLVLSFLQLHPR--------SKS-GR----LA-------------V------LKNLGVLLIKFFELYGNFGYDKLGISLSLGGEYVSKELTGLSIEDPVDPTNDIGRSS--FNFSQVKGAFAYAFKVLTNAVFSHGSSSLYRTERDQGFNKRNMPGPTDSPSVNPNETGSEPSSGTGASIPENSHSPVTDSPRSKGSGYSS | |
| cd05402 | 99.93 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KREEVLDRLQELIKEWFPGAKLYPFGSYVTGLGLPGSDIDLCLLGPNH------------------------RVDREDFLRKLAKLLKKSGE-VVEVEPIINARVPIIKFVDKPTGIEVDISFNNLNGIRNTKLLRAYV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| PTZ00418 | 99.84 | |
------------------------------------------------------------------------------------------------------MHTVYESENLLSNFELSSKLSIEAFSQLSSSKSENEETY-L-----------SYSIECA-LS-YGVTDPISLNGPT--EEDLKLSNELINLLKSLYETEEGKKKRERVLGSLNKLVREFIISGKLFTFGSYRLGVVAPGSDIDTLCLAPRHITR-------------------------ESFFSDFYAKLQQ-DPNITKLQPVPDAYTPVIKFVYD--GIDIDLLFADDNGCRVADLILASVPNKDYFRTTLRFIKLWAKRRGIYSNVL-GYLGGVSWAILTARICQL------------YP----------------------------N-FAPSQLIHKFFRVYSIWNWKNPVL-LCKGLMFKVWDAHLMPIITPAFPSMNSTHNVTYTTKRVITEEFKRAHEIIKYIEKN-----SENTWTN--VLEPLDFFTSVIYHNKWEGWIESKIRFLIKKLETPYPKFFKYQDNTFDLRYAI | |
| d2q66a2 | 99.80 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------KVFGITGPVSTVGAT--AAENKLNDSLIQELKKEGETEQETANRVQVLKILQELAQRFDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVT-------------------------REDFFTVFDSLLRER-KELDEIAPVPDAFVPIIKIKF--SGISIALICALSLTLSDKNLLRN---LDEKLRALN------------------GTRVTDEILELV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | |
| d1q79a2 | 99.72 | |
---------------------------------------------------------------------------------------------------------------------------------------------------HY--------GIT--------SPISLAAPKE---TDCLLTQKLVETLKPFFEEEEELQRRILILGKLNNLVKEWIVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVD-------------------------RSDFFTSFYDKLKLQ-EEVKDLRAVEEAFVPVIKLCF--DGIEIDILFPEDLDLRDDSLLKN---LDIRIRSL------------------NGCRVTDEILHLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | |
| pfam0382 | 99.43 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLGELLIGFFEYYGEFDYEKVVISIRTGGYLSKKEKSPLCIEDPFD----------------------------------------------------------------------------------------------------- |
PSI-BLAST run over PDB70 database (4 iterations)
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 3hj4 A | 7.61815e-79 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISL------------TYRNFSPWLQ----GMERVDEQNNKRMTRFGKEASAMGMEDVR-YIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILAIRQVFPDFYGAYIHLVKAWGKAREVIAPERSTF-NSFTVTTMALMVLQELG--LLPVFSKPTELTVADAEMLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRH--RTVYERVVRRHLELLGSRKRLEWEKHIAEHKEDGNDFSASMQNETTQRP---SNSPY--------------------------------------------------------- | |
| 4fh3 A | 3.51038e-75 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------SYQKVPNSHKE-FTKFCYE---------VYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDS--------------------RVQSDTIALQFYEELIAEGFEG--------KFLQRARIPIIKLTSDGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPYFGT-LSSYGYVLMVLYYLHVIKPPVFPNL----LLSPLKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPADQIIKDRYILAIEDPFEISHNVGRTVSSSGLYR------------------------------------------------------------------------------------- | |
| 2q0d A | 3.20532e-72 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVNSFKQFVSKDLHTRHVDATYRLVLDCVAAVDPLMRLYTFGSTVVGVHEKGSDVDVVLNKTDVEDGKGGDAATQVAKGLQADILAKARVIRQKHLSWNVEEVRRTRVPVVRVK--------------GGGAVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQFVPPST------------IDVSRVEPLPPHLPLE-EPADEGLELGTQDFLHFFHEFDSDKQVISLNRPRMNGEKVHYQWCIEDPYELNLNVGRNVTPLKLRRHLEKARDTA---------------------------------------------------------------------------- | |
| 1q79 A | 1.53155e-58 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILGKLNNLVKEWI--REISESKNLPQSVIENVGGKIF------TFGSYRLGVHTKGADIDA--LCVAPRHVDRSDFFTSFYDKLKLQEEVKDRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILG-FLGGVSWAMLVARTCQVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSD--------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 3nyb A | 2.10356e-57 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKEISDWLTFEIKDFVASREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVLGGKESRN-----NLYSLASHLKKKNLATE------------------------VEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGG-LGGFSIICLVFSFLHMH-PRIIT----------------------------NEIDPKDN---LGVLLIEFFELYGNFGYDDVALGSSDGYPVYFPKSFSLAIQDPGDESNNISRG--------------------------------------------------------------------------------------------- | |
| 2q66 A | 1.09004e-51 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVSKKKNMSDGMARDAGGKIF------TYGSYRLGVHGPGSDIDTLV--VVPKHVTREDFFTVFDSLLRERKELDEIAVPDAFVPIIKIKFSGISIALICARLDQPQVPLSLTLSDKNLLRNLDEKDLRANGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFG-FPGGVAWAMLVARICQLYRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKI------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 2b4v A | 8.57259e-46 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIAIQCTSKEQMIEAIGFFPDG-KIMTRGMREDYTRDVLDVRFVPEMFMYRWDISFVGY-GVKNSYLIRHYLHNGPAARHTAMAVKAWGKATNVGAG-SGAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPA-----------HLPRYPDFSPLYDCDPTE-LGRLLHGFFIFYHHFDYEREVVSLNRNRRSYRSDSYNFCIEDPYEDGLNLVRHLHPAKFQ-------------------------------------------------------------------------------------- | |
| 1no5 A | 0.0256803 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKSEELAIVKTILQQLVPDYTVWAFGSRVKGKAKKYSDLDLAIISEEPLDFLARD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 2rff A | 0.676189 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESQIRMLKLAKEIVEEVASSFPNLEEVYIFGSRARGDYLDTSDIDILFVFKGIKEMNVFDRMYMVSRFIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | |
| 3dup A | 4.16891 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLMLLDRAVVPTFGVRAYGVHLNGYVGAGADLHLWIGRRSPDKSVAPGKLDNMVAGGQ----PADLSLRQN---LIKECAEEADLPEALARQAIP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
PSI-BLAST run over CullPDB database (4 iterations)
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 4fh3 A | 1.04473e-17 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARIPIIKLTSDGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPYFGT-LSSYGYVLMVLYYLHVIKPPVFPNL----LLSPLKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRSADQIIKDRYILAIEDPFEISHNVGRTVSSSGLYR------------------------------------------------------------------------------------- | |
| 3nyb A | 3.69562e-05 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEISDWLTFEIKDFVASREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVLGGKESRNLASH---------LKKKNLATE------------------------VEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGG-LGGFSIICLVFSFLHMH-PRIIT----------------------------NEIDPKDN---LGVLLIEFFELYGNFGYDDVALGSSDGYPVYFPKSTSLAIQDPGDESNNISRG--------------------------------------------------------------------------------------------- | |
| 2q0d A | 4.0848e-05 | |
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQR-------------------------NHLQFVPDVSRVEPEPADEGLELGTQDFLHFFHEFDSDKQVISLNRARMNGEKVHYQWCIEDPYELNLNVGRNVTPLKLRRHLEKARDTA---------------------------------------------------------------------------- | |
| 3hj4 A | 8.51239e-05 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILAIRQVFPDFYGAYIHLVKAWGKAREVIAPERSTF-NSFTVTTMALMVLQELG--LLPVFSKPTTVADAE--MLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRH-------------------------------------------------------------------------------------------------------------------- | |
| 3hjl A | 3.76326 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAVLLLSLPEEVSMNIVKELSEEELQKLFALAKD------------------------------------------------------------------------------ | |
| 3deu A | 4.79347 | |
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARLVRIWRALDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGI------EQPSLVRTLDQL------EDKGLISRQTCASDRRAKRIKLTEKAEPLIAEMEE------------------------------------------------------------------------------------------------------------------------------------------- |
PHYRE - remote method
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 2q0d B | 5.8e-25 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHSSGLVPRGSHMPPSPAVVGRSLVNSFKQFVSKDLH-TRHVDATYRLVLDCVAAVDPLMRLYTFGSTVYGVHEKGSDVDFVVLNKTDVEDGK----------GGDAATQVAKGLQADILAKLARVIRQKHL-SWNVEEVRRTRVPVVRVKG-GGAVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNH----------LQFVPPSTIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQVISLNRPGITTKKVHYQWCIEDPYELNLNVGRNVTPLKRDFLRRHLEKARDT-------------------------------------------------------------------------- | |
| 1f5a A | 2.4e-17 | |
---------------------------------------------------------------------------------------------------------------------------------------------------PFPVTTQGSQQTQPPQKHYGITSPI--SLAAPKETDCLLTQKLVETLKGVFEEEEELQRRILILGKLNNLVKEWNVGGKIFTFGSYRLGVHTKGADIDALCVAPRH-------------------------VDRSDFFTSFYDKLKLQE-EVKDLRAVEEAFVPVIKLCFDG--IEIDILFASLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNIL-GFLGGVSWAMLVARTCQLYPNTLVHKFFLVFSKWEWPNPVLL----------------------------------KQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAE---------------------------------------------------------------- | |
| 2q66 A | 1.4e-16 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAAENKLNDSLIQELKGSFETEQETANRVQVLKILQELAQRFDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKH-------------------------VTREDFFTVFDSLLRE-RKELDEIAPVPDAFVPIIKIKFS--GISIALICRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIF-GFPGGVAWAMLVARICQLYPNACSAVI--LNR----------------FFI-----------------------ILSEWNWPQPVIRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDNKKSWANLFEKNDF--------------------------------------------------------- | |
| 2b4v A | 2.2e-14 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------SPLSLP--STKLNPSPDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMTYGQMERGSDLDTALLDVRNQCVGDNDVEYIAEKMGRDNVEGIRVDRTTYGCRIEAIGFFPDGKIMTRGMREDYTRDVLVRFVPEMFMYRWDISFVG-YGVKNSYLIRHYLHNGPAARHTAMAVKAWGKATNVGAGS-GAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHLPRYPD-----------FSPLYDCDPTELGRLLHGFFIFYAHHFDYEREVVSLNRNRRSYRTFSYNFCIEDPYEGGLNLVRHLHPAKFQLVKQEFLRAAQCMERFLPTNAPEK-------------------------------------------------------------- | |
| 2b4v A1 | 6e-11 | |
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AARHTAMAVKAWGKATNVGAGS-GAMLTSYAVTVMFIYYLLVTRQVLWVDPWSL------PHPAHLPRY-----PDFSPLYDCDPTELGRLLHGFFIFYAHHFDYEREVVSLNRNRRSYRTFSYNFCIEDPYEGGLNLVRHLHPAKFQLVKQEFLRAAQCMERFLPTNAP---------------------------------------------------------------- | |
| 1tfw C | 8e-07 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEEILEKALELVIPDEEEVRKGREAEEELRRRLDEL--GVEYVFVGSYARNTWLKGLEIDVFLLFP---------------------EEFSKEELRERGLEIGKAVLDSYEIRYAEHGVVKGVEVDVVPCYKLKEPKNIKSAVDR--TPFHHKWL---EGRIKGKENEVRLLKGFLKANGIYGAYKVRGFSGYLCELLIVFY---------GSFLET-------------------VKNARRWTRRT------------------------VIDVAKG---EVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHL---CREFMEAPSFKPKHPLEIEPERLRKIV--------------------------------------------------- | |
| 2hhp A1 | 8.5e-07 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPNVFRIALRAIKLWAQRRAVYAN-IFGFPGGVAWAMLVARICQLYPNAILNRFFIILSEWNWPQPVIL----------------------------------KPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKS---------------------------------------------------------------- | |
| 1q79 A1 | 1.8e-06 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIDNFRLTLRAIKLWAKRHNIYSN-ILGFLGGVSWAMLVARTCQLYPNTLVHKFFLVFSKWEWPNPVLL----------------------------------KQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAE---------------------------------------------------------------- | |
| 1q79 A2 | 6e-06 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KETDCLLTQKLVETLKGVFEEEEELQRRILILGKLNNLVKEWNVGGKIFTFGSYRLGVHTKGADIDALCVAPRH-------------------------VDRSDFFTSFYDKLKLQE-EVKDLRAVEEAFVPVIKLCFD--GIEIDILFARLA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 2hhp A2 | 8e-06 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAAENKLNDSLIQELKGSFETEQETANRVQVLKILQELAQRFDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDF-------------------------FTVFDSLLRERK-ELDEIAPVPDAFVPIIKIKFSG--ISIDLICARLDQPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
FFAS - remote method
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 3pq1 A | -87.7 | |
----------------------------MGSSSSGLVPRGSHMEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTP------------------------------XXXXXXXSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCALTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAXXXXXXXXXXXXXXXRESAWILQQEDTDRPSISSNRPWG---LVSLLLPSAPN----------------------------------------------------------------------------- | |
| 2ikf A | -75.2 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHMPPSPAVVGRSLVNSFKQFVSKDLHTRHVDATYRLVLDCVAAVDPLMRLYTFGSTVYGVHEKGSDVDFVVLNKTDVEDGKGGDA----------ATQVAKGLQADILAKLARVIRQKH-LSWNVEEVRRTRVPVVRVKGG-GAVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQFVPPSTIDVSR-----------VEPLPPHLPLEEPADEGLELGTQVLDFLHFFLEFDSDKQVISLNRPGITTKEELDWWCIEDPYELNLNVGRNVTPLKRDFLRRHLEKARDTALLT---------------------------------------------------------------------- | |
| 4fh3 A | -73.2 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HMSYQKVPNSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSD----------------------------TIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPY-FGTLSSYGYVLMVLYYLIHVIPPVFPNLLLSPL----KQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPDGYLTKQRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEE---------------------------------------------------------- | |
| 4ep7 A | -73.1 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSD----------------------------TIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPY-FGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSP---LKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPDGYLTKQRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEE---------------------------------------------------------- | |
| 4e7x A | -72 | |
-------------------------------------------------------------------------------------------------------------------------------------------------SSAQFIPGVHTVEEIEAEIHKNLHISKSCSYQKVPNSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSD----------------------------TIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPY-FGTLSSYGYVLMVLYYLIHVIPPVFPNLLL----SPLKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPDGYLTKDRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEEAPIPPRRQKKTDEQSNKKLLNETDGDNSE----------------------------- | |
| 3hj1 A | -71.1 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHMNVAKREFIRGMMAHYRASLPPPEHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISLTYRNFSP-----------------WLQGMERVDEQNNKRMTRFGKEASAMGMEDVRYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILCAIRQVFPDYGAYIHLVKAWGKAREVIAPE-RSTFNSFTVTTMALMVLQE--LGLLPVFSKPTGEFGEDAEMLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRHRTVYENSPYVVEDFVNYVNCGRRVQASRVRHIQQEFNRLREMLIDKES-------------------------------------------------------------------- | |
| 3nyb A | -69.5 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELG------------------------GKESRNNLYSLASHLKKKN-LATEVEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVH-TGGLGGFSIICLVFSFLHMHPRIITNEID--------------------------------PKDNLGVLLIEFFELYGNFGYDDVALGSSDGYPVYFPKSFSLAIQDPGDESNNISRGSFN--IRDIKKAFAGAFDLLTNRCFELHSATFKDGKSILGNVIK------------------------------------------------- | |
| 2b4v A | -64 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKLNPSPDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMTYGQMERGSDLDLACMFDDPYPSHEVQAKRTDKLRTVIKRIAIQCTSKEQMIEAIGFFPDGKIM-TRGMREDYTRDVLDVRFVPEMFMYRWDISFVG-YGVKNSYLIRHYLHNGPAARHTAMAVKAWGKATNVGAGS-GAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHLPRYPDFSPL------------YDCDPTELGRLLHGFFIFYAHFDYEREVVSLNRNRRSYRSDIGWFCIEDPYEDVGNLVRHLHPAKFQLVKQEFLRAAQCMERFLPTNAPEKS------------------------------------------------------------- | |
| 1q78 A | -47.1 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETDCLLTQKLVETLKPF--GVFEEEEELQRRILILGKLNNLVKEWIVGGKIFTFGSYRLGVHTKGADIDALCVAPR-------------------------HVDRSDFFTSFYDKLKLQE-EVKDLRAVEEAFVPVIKLCF--DGIEIDICIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNIL-GFLGGVSWAMLVARTCQLYP-----------------------------------------NAIASTLVHKFFLVFSKWEWPNPVLKQPEECNLPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDE----------------------------------------------------------------------- | |
| 2o1p A | -47.1 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAENKLNDSLIQELKKE--GSFETEQETANRVQVLKILQELAQRFVAGGKIFTYGSYRLGVHGPGSDIDTLVVVPK-------------------------HVTREDFFTVFDSLLRERK-ELDEIAPVPDAFVPIIKIKFSGISIDLEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIF-GFPGGVAWAMLVARICQLYP-----------------------------------------NACSAVILNRFFIILSEWNWPQPVIRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITND----------------------------------------------------------------------- |
mGenThreader
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 3pq1 A | 4e-16 | |
-------------------------------------------------------------RFSEMQNERREQAQRTVLIHCPEK---NKFLKYLSQFGPINNHFFYESFGLYAVVEFCS-----------------------------------IGSLQNGTHT-------NKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDSAHKISGMEFQV--------KNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCALTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTS--SGAWITNFSLTMMVIFFLQRRSDSLKTLAD----------------------------AESQNTETLELLLKEFFEYFGNF---------------------------------------SQSQLQKFVDLARESAWILQQE-----------PWGLVSLLL-------------------------------------------------- | |
| 3hj4 A | 1e-10 | |
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAKREFIRGMMAHYRASLPPPEHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISLTYRNFSP-----------------WLQGMERVDEQNNKRMTRFGKEASAMGMEDVRYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILCAIRQVFDFYGAYIHLVKAWGKAREVIAP-ERSTFNSFTVTTMALMVLQELGPVFSKPTGEFGELTVADAEMLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRHTQRPSNSPYVVEDFVNYVNCGRRVQASRVRHIQQEFNRLREMLIDKESELKESDT------------------------------------------------------------- | |
| 3hj4 A | 2e-10 | |
---------------------------------------------------------VAKREFIRGMMAHYRASL-------PPPEHSVVIHELQKRVLDIGMLAVNKA----HVELFG---------------SHVSGFCTPHSDADISLTYRNFS------PWLQGMERVDEQNNKRMT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 2q0d A | 3e-10 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSPAVVGRSLVNSF---KQFVSHVDATYRLVLDCVAAVDPLMRLYTFGSTVYGVHEKGSDVDFVVLNKTDVEDGKGGDA----------ATQVAKGLQADILAKLARVIRQKHLSWN-VEEVRRTRVPVVRVKGGG-AVDFDITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQFVPP----------STIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQVISLNRPGINGEKVHYQWCIEDPYELNLNVGRNVTPLKRDFLRRHLEKARDTALLTIV-------------------------------------------------------------------- | |
| 3nyb A | 3e-09 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------GSYPWILNHDHSKQKE-----------ISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELG------------------------GKESRNNLYSLASHLKKK-NLATEVEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTG-GLGGFSIICLVFSFLHMHPRIIT-----------------------------NEIDPKDN---LGVLLIEFFELYGKFGYDDVALGSSDGYIQPIKNPFSLAIQDPGDESNNISRGSF--NIRDIKKAFAGAFDLLTNRCFELHSATFKDRLG--KSILGNVIKY-------------------------------------------- | |
| 3nyb A | 4e-09 | |
------------------------------------------GSYPWILNHDHSKQKEISDWLTFEIKDFVAYIS-------PSREEIEIRNQTISTIREAVKQLWPDAD----LHVFG---------------SYSTDLYLPGSDIDCVVTSEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 2b4v A | 1e-08 | |
------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPS--------PDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMVTGQMERGSDLDLACMFDDPYPSHEVQAKRTDKLRTVIKRYVPHYLRN-------------------NLLGLTEARTPVVKLRFEMFMYRWDISF-VGYGVKNSYLIRHYLHNGPAARHTAMAVKAWGKATN------GAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHLPRYPDFSPLY------------DCDPTELGRLLHGFFIFYAHFDYEREVVSLNRNRGWNFPQNYNFCIEDPYEDGLNLVRHLHPAKFQLVKQEFLRAAQCMERFL--PTNAPEKSILG-------------------------------------------------------- | |
| 1q79 A | 8e-06 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------HYGITSSLAAPK---------ETDCLLTQKLVETLKPFGVEEEELQRRILILGKLNNLVKEWNVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVD-------------------------RSDFFTSFYDKLKL-QEEVKDLRAVEEAFVPVIKLCFD--GIEIDILFARLAGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNIL-GFLGGVSWAMLVARTCQLYPNAI-----------------------------------------ASTLVHKFFLVFSKWEWPNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAE------WSKLFEAPNFFQKYKGLVESK--------IRILVGSLEKN--EFNPQSAPKENPDKEE | |
| 2q66 A | 1e-04 | |
-------------------------------------------------------------------------------------------------------------------------------------------------------------------KVSTVGAT---------AAENKLNDSLIQELKKEFETEQETANRVQVLKILQELAQRFVAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVT-------------------------REDFFTVFDSLLRE-RKELDEIAPVPDAFVPIIKIKFS--GISIALICARLDGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANI-FGFPGGVAWAMLVARICQLYPNAC-----------------------------------------SAVILNRFFIILSEWNWPQLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKS---------------------------------------------------------------W | |
| 1r89 A | 0.002 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVE--YVFVGSYARNTWLKGSEIDVFLLFPEEFS-------------------------KEELRERGLEIGKAVLDS----YEIRYAEHPYVHGVVKGVEVDVVPCYKIKSAVDRTPFHHKWLERIKGKENEVRLLKGFLKANGIYGAYKVRGFSGYLCELLIVFYGS------------------------------------------------------FLETVKNARRWTRRIDVAKGGE-------EFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEA---------------------------PSLGFFKPKHPLEIEPERLRKIVEERGT------------------A |
PCONS5
| 1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580 | ||||
| pdbid | score | model | MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPINNHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAEDKCVIEGNNCTFVRDLSRIKPSQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRPSISSNRPWGLVSLLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT | |
| 4fh3 A | 1.6599 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------SYQKVPNSHKE-FTKFCYE---------VYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDS--------------------RVQSDTIALQFYEELIAEGFEG--------KFLQRARIPIIKLTSDGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPYFGT-LSSYGYVLMVLYYLHVIKPPVFPNL----LLSPLKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPADQIIKDRYILAIEDPFEISHNVGRTVSSSGLYR------------------------------------------------------------------------------------- | |
| 1r89 A | 1.544 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVE--YVFVGSYARNTWLKGSEIDVFLLFPEEFS-------------------------KEELRERGLEIGKAVLDS----YEIRYAEHPYVHGVVKGVEVDVVPCYKIKSAVDRTPFHHKWLERIKGKENEVRLLKGFLKANGIYGAYKVRGFSGYLCELLIVFYGS------------------------------------------------------FLETVKNARRWTRRIDVAKGGE-------EFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEA---------------------------PSLGFFKPKHPLEIEPERLRKIVEERGT------------------A | |
| 3hj4 A | 1.4592 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISL------------TYRNFSPWLQ----GMERVDEQNNKRMTRFGKEASAMGMEDVR-YIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILAIRQVFPDFYGAYIHLVKAWGKAREVIAPERSTF-NSFTVTTMALMVLQELG--LLPVFSKPTELTVADAEMLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRH--RTVYERVVRRHLELLGSRKRLEWEKHIAEHKEDGNDFSASMQNETTQRP---SNSPY--------------------------------------------------------- | |
| 3hj4 A | 1.3023 | |
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAKREFIRGMMAHYRASLPPPEHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISLTYRNFSPWLQ----------------GMERVDEQNNKRMFGKEAS--AMGMEDV-RYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILCAIRQFPDFYGAYIHLVKAWGKAREVIAPE-RSTFNSFTVTTMALMVLQEL--GLLPVFSKPTG---EFGELTVADAEMLLQE--FKLPLHDDDEKLGEALQRFAEYYAKYDFSAGTVSLIHPRRHREWEKSPYVVED-FVNYVNCGRRVQASRVRHIQQEFNRLREMLIDKESEL---------KFDEVFRESDTVP-------------------------------------------- | |
| 3hj1 A | 1.296 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHMNVAKREFIRGMMAHYRASLPPPEHSVVIHELQKRVLDIGMLAVNKAHVELFGSHVSGFCTPHSDADISLTYRNFSP-----------------WLQGMERVDEQNNKRMTRFGKEASAMGMEDVRYIRARIPVVQFTDGVTGIHCDVSIGNIGGVENSKILCAIRQVFPDYGAYIHLVKAWGKAREVIAPE-RSTFNSFTVTTMALMVLQE--LGLLPVFSKPTGEFGEDAEMLLQEFKLPPIYDSLHDDDEKLGEAVFFCLQRFAEYYAKYDFSAGTVSLIHPRRHRTVYENSPYVVEDFVNYVNCGRRVQASRVRHIQQEFNRLREMLIDKES-------------------------------------------------------------------- | |
| 2q66 A | 1.2054 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVSKKKNMSDGMARDAGGKIF------TYGSYRLGVHGPGSDIDTLV--VVPKHVTREDFFTVFDSLLRERKELDEIAVPDAFVPIIKIKFSGISIALICARLDQPQVPLSLTLSDKNLLRNLDEKDLRANGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFG-FPGGVAWAMLVARICQLYRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKI------------------------------------------------------------------------------------------------------------------------------------------------------------- | |
| 4fh3 A | 1.2016 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HMSYQKVPNSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSD----------------------------TIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPY-FGTLSSYGYVLMVLYYLIHVIPPVFPNLLLSPL----KQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPDGYLTKQRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEE---------------------------------------------------------- | |
| 3nyb A | 1.1862 | |
----------------------------------------------------------------------------------------------------------------------------------------------------------------------GSYPWILHDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELGGK------------------------ESRNNLYSLASHLKKK-NLATEVEVVAKARVPIIKFVEPHSGIHIAVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHT-GGLGGFSIICLVFSFLHMH-PRIITN-------------------------EI------DPKDNLGVLLIEFFELYGNFGYDDVALGSSDGYPFPKSTPFSLAIQDPGDESNNISRG--SFNIRDIKKAFAGAFDLLTNRCFELHSATDRLGKSILGNVIKY------------------------------------------------ | |
| 4ep7 A | 0.9893 | |
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSD----------------------------TIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPY-FGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSP---LKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAKFEPREKVVTFRRPDGYLTKQRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEE---------------------------------------------------------- | |
| 2rff A | 0.9889 | |
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESQIRMLKLAKEIVEEVASSFPNLEEVYIFGSRARGDYLDTSDIDILFVFKGIKEMNVFDRMYMVSRFIR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ |
b) disorder predictors:
DISOPRED2 result file
DISpro result file
DISPROT (VSL2) result file
GlobPlot result file
iPDA result file
IUPred long result file
IUPred short result file
Pdisorder result file
Poodle-l result file
Poodle-s result file
PrDOS result file
RONN result file
Spritz long result file
Spritz short result file
DisEMBL coils result file
DisEMBL hotloops result file
DisEMBL remark465 result file