Modomics - A Database of RNA Modifications

General Data

RNA Type tRNA
SOTerm SO:0000264
Original Source tdbR00000269
Secondary Structure (((((((..(((...........)))((((((.......))))))((((....)))).(((((.......))))))))))))....
Sequence (UNICHARACTER ENCODING) GUCAGLAUGLCMGAGUGGDCPAAGGCRCCAGACU..AKKPPUGGJJPPCGGAUGGAG??UGGGTTPGѢѢUCCCACUUCUGACACCA
Sequence (SHORT NAMES ENCODING) GUCAGpm2GAUGpm2GCpac4CGAGUGGpDCpYAAGGCpm2,2GCCAGACUNNApm1Gpm1GpYpYUGGpUmpUmpYpYCGGAUGGAGpm5Cpm5CUGGGpm5Upm5UpYGpm1Apm1AUCCCACUUCUGACACCA
Sequence (MODOMICS CODE ENCODING) GUCAG2000002551GAUG2000002551GC2000042551CGAGUGG2000008551UC2000009551UAAGGC2000022551GCCAGACU2000000000N2000000000NA2000001551G2000001551G2000009551U2000009551UUGG2000090551U2000090551U2000009551U2000009551UCGGAUGGAG2000005551C2000005551CUGGG2000005551U2000005551U2000009551UG2000001551A2000001551AUCCCACUUCUGACACCA
Consensus Secondary Structure .(((((((..((((......[....)))).(((((.......)))))........................(((((..]....))))))))))))....
Alignment with Modification -GUCAGLAUGLCMGAGU--GGDCPAAGGCRCCAGACU..AKKPPUGGJJPPCGGAUGGAG?----------?UGGGTTPGѢѢUCCCACUUCUGACACCA

Score Table

Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.
Method Classification Score
Multiple direct experimental evidence 1
Direct experimental evidence 2
Inferred based on indirect experimental evidence 3
Predicted computationally 4
Evidence not yet annotated (Unknown) 5
Irrelevant 6

RNA-2D Representation

RNA Secondary Structure

RNA Consensus Secondary Structure

Modification Positions

Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.

Position in the alignment 6 10 12 20 20B 26 34 35 37 38 39 40 44 45 45A 45B 45L 49 54 55 56 58 59
Position in the sequence 6 10 12 19 21 27 35 36 38 39 40 41 45 46 47 48 58 59 64 65 66 68 69
Modification positions m2G m2G ac4C D Y m2,2G N N m1G m1G Y Y Um Um Y Y m5C m5C m5U m5U Y m1A m1A
Level of Experimental Evidence 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Level of Experimental Reliability 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
Source MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS MODOMICS