Genesilico metadisorder service
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Results for job: CPSF5_HUMAN

All residues whose disorder probability is over 0.5 are considered as disordered.
For visibility only 4 plots corresponding to predictions  from final metapredictions had been shown. To see results from primary methods click on the shadowed  name of method in legend (the left side of plot).

Alternatively you can see results in simple text format here


Short description of  meta methods:
MetaDisorderMD2 -CASP9 winning method (group number 147) - a method based on 13 disorder predictors and gaps in alignment produced by 8 fold recognition methods, optimized by Sww score (see Help page for details) using genetic algorithm. If you are looking for the most accurate disorder predictor, you should use this one, according CASP9 its AUC is 0.839; MetaDisorderMD2 result file casp_logo
MetaDisorderMD - (group 374, fourth place in CASP9), AUC 0.816, similar to MetaDisorderMD2, but during optimization via AUC is 0.839; MetaDisorderMD result file casp_logo
MetaDisorder - CASP8 winning method (group 153 in casp8, and group 010 in casp9) - metaprediction based on 13 disorder predictors AUC is 0.839; MetaDisorder3D result file casp_logo
MetaDisorder3D - (group 421), counts gaps as disorder in top ten alignments produced by 8 different fold recognition methods, method and alignment efficiency to detect disorder was optimized by GA, tested during CASP9 as a reference to other meta methods, results are far AUC is 0.839; MetaDisorder result file casp_logo

Primary predictors used by meta methods:
a) fold recognition methods:
HHsearch run over pdb70 database    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2xsq A  97.61    --------------------------MHHHHHHSSGVD--------LGTENLY---FQSMAARRLELGEALALSGWRHVCHALLYAGRIPLRYAILMQMFDGRLGFPGGFVDTQDSLEDGLNRELREELGEAAAAF-RVERTDYRSSHVGSG---------------PRVVAHFYAKRLTLEELLAVEAGLGLVRVPLYTLRDGV-------GGLPTFLEN-SFIGS
1u20 A  95.77    ----------------MAE----------SR-----------------SPD-RGAKEDKPRPRNISREESLQLEGYKHACHALL-HAPSQIRRVLLMMMFDGRLGFPGGFVDTRDSLEEGLKRELEEELGPALAT-VEVTEDDYRSSQVR------EHP--------QKCVTHFYIKELKLEEIERIVEVMGLIRVPLYTLRDR-------VGGLPAFLC-NNFIGN
2fvv A  95.62    --------------------------MHHHHHHSSGVD--------LGTEN---LYFQSMMKLKSNQTRTYDGDGYKKRAACLCFRSESE-EEVLLVSSSPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKG------TLGRLVGIFENQERK---------------HRTYVYVLIVTEVLE-DWEDGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGATTYS
3f13 A  95.32    ---------------------------------------------------------MSLEDRNERLPS-------DLARRATAIIEMPD--GVLVTASRGGRYNLPGGKANRGELRSQALIREIREETGLRIN------SMLYLFDHITPFN--AHKVYLQGQPKPQNEIERIALVS-SPDTDMDLFVEGRAI-LR--RYARLRNEETAKGEALRALLGLARYIAK
1ktg A  94.59    ---------------------------------------------------------------------------MVKAAGLVIYRKLAGKIEFLLLQASYPHWTPPKGHVDPGEDEWQAAIRETKEEANITKE---QLTIHDCHET-LFYEAK---------G---KPKSVKYWLAKLNNPDDVQLSHHQNWKWCELEDAIKIYAEMGSLLRKFSAFLAGF-----
1vcd A  94.47    ---------------------------------------------------------------------------MELGAGGVVFNAKR---EVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGVRAEV------LLPLYPT--------RYVN--PK---GVEREVHWFLMRGEGAPRLEEGMTGAGWFSPEEARALL-AFPEDLGLLEVALERLPL---
3eds A  94.45    ---------------------------------------------------------MSLSLYYKKIREQLGHELIFXSVAAV-IKNEQG--EILFQYPGGEYWSLPAGAIELGETPEEAVVREVWEETGLK------VQVKKQKGVFGGKEYRY-TYSN----GDEVEYIVVVFECEVTS-GELR-SIDGESLKLQYFS-----------LSEKPPLALPYDKILE
3kvh A  94.24    ----------------------------------------------------------MVPEKQISRVEAMRGPGWSHSCHAMLYAGRIPMRFSVLMQMRDGLLGFPGGFVDRRFSLEDGLNRVLGLGLGCL-----RLTEADYLSSH------LTEGP---HRV-----VAHLYARQLTLEQLHAVEEVLGLVRVPLYTQKDRV-------GGFPNFLSN-AFVST
3gz5 A  94.18    -----------------------------------------------GSHMTEAE-------YL----ANYDPKAQLLTVDAVLFTYHDQQLKVLLVQRSNGLWGLPGGFIDEDESLEQTVLRKLAEKTAVVPPYI------EQLCTVGNNSRDAVYTALMSYQAIQIASVSDVKWWPLADVLQMPLAFDHQLIEQARERLT-QKALYSLVPGFAPELQHVHEVLLG


HHsearch run over CDD database    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
d1puna  96.44    ---------------------------------------------------------------------------MKKQIAVGIIRNENN--EIFITRRAANKLEFPGGKIEMGETPEQAVVRELQEEVGITPQ------HFSLFEKYEFPDRHITLWFWLVERWEWGKEGQPGEW-------------------MSLVGLNAFPPANEPVIAKLKRL---------
d1u20a1  96.42    --------------------------------------------------------DKPRPRNISR-EESLQLEGYKHACHALLHAPSQIRRVLLMMMRFDGRLGFPGGFVDTRDISEEGLKRELEEELGPALATV-EVTEDDYRSSQVRE---H-----------PQKCVTHFYIKELKLEEADHGLEVMGLIRVPLYTLRDRV-------GGLPAFLCN-NFIGN
cd03428  96.40    ---------------------------------------------------------------------------EERSAGAIIYRRLNNEIEYLLLQASYGHWDFPKGHVEPGEDDLEAALRETEEETGITAEQL------FIVLGFKTLNY-----QV-----RGKLKTVTYFLAELRPDVEVKLSEHQDYRWLPYEEALKLL-TY----EDLKAVLDKAHA---
d2fvva1  96.26    ------------------------------------------------------------------QTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKG------TLGRLVGIFENQERKHRVYVLIVTEVLE-----------------DWEDSVNIREWFKIEDAIKVLQYHKPVQASYF--ET-------
d1k2ea  96.05    ---------------------------------------------------------------------------MIVTS-GV-LVEN---GKVLLVKHKLGVYIYPGGHVEHNETPIEAVKREFEEETGIVVEP------IGFTYGIIDENAVERPMPLEETHIRVGGDLKNGEWIDVREIDRIETFPNVRKVVSLALSTLYRLGKI----SKLAAALEHH-----
d1nqza  95.98    ----------------------------------------PHDP----LDDIQADPWALWLS--GRTRTALELPHYRRAAVLVALTR-EADPRVLLTVRSKGQIAFPGGSLDAGETPTQAALREAQEEVALDPAAV------TLLGELVFTPVGFHVTPVLLDTLRVTPEVAQIITPTLAELRAVPLVPDGTEVPLYRYP-WRGLDIWGMTARVLHDLLE-------
cd04667  95.93    -------------------------------------------------------------------------------ERATVICRRGG--RVLLVRKSGSRWALPGGKIEPGETPLQAARRELQEETGLQGLDL------LYLFHVDGG--STRH---------------HVFVASVPPSAQPKPSEIADCRWLSLDALGD------LNASAATRLIVR------
d1ktga  95.84    ---------------------------------------------------------------------------VVKAAGLVIYRKLAGKIEFLLLQASPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTI-----HEDCHETLFYEAKGKPK----------SVKYWLAKLNNPD--DVQLSHEHQNCELEDAYAEM---GSLLRKFSAFLAGF-----
d1vcda1  95.53    ---------------------------------------------------------------------------MELGAGGVVFNA-KR--EVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGVRAE------VLLPLYPYVNPKGVE-------------R-EVHWFLMRGEG--APRLEEGMGAGWFSPEEARAL-LAFPEDLGLLEVALERLPL---


PSI-BLAST run over PDB70 database (4 iterations)    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3bho A  1.41234e-126    -------------------FGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2du3 A  0.00972734    ----------------------------KEILAERSPNLYPRVGFSFGKEHPLF-------ATIQRLREAYLSIGFSEVVNPLIVEDVH------------------------------------------------------------------------------------------------------------------------------------------
3dgt A  0.173042    ---------------------------------------------------------------------------------------------------GTSY---PGGAGNWGTGEVESMTSSTSNVSLDGNGDLLITPRRDASGNWTSGRIETTRTDFQPPAGGKLRVEARLQMPNVTGDAAAGYWPAFWMLGAPFRGNYQNWPGVGEL----------------
3id9 A  1.42868    --------------------------------------------------------------KFNRKRRLYIENIMQVRVTGILIEDE----KVLLVKVANRDWSLPGGRVENGETLEEAMIREMREETG-------------------------------------------------------------------------------------------------
2ctz A  1.6057    --------------------------EPEPTTLSRQVPIYPTTSYVFKSPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1v8y A  1.61915    ---------------------------------------------------------------------------------AVIALREGRMLFVRQMRVGLAPLEIPAGLIEPGEDPLEAARRELAEQTG-------------------------------------------------------------------------------------------------
3gzi A  1.89731    -------KSRVGRPSGDTQNRDKLILAARNLFIERPYAQVSLIRYYFGSKEKLFETAMPVLAQLHKARRETRQAALLQTYYSVMSKHPH-FPRLML-----------------------------------------------------------------------------------------------------------------------------------
3mxm A  1.9132    ----------------------------------------------------------------------------------------------------------PGKACSPGASEITGLSKAELEVQGRQ-----------------------------------------------------------------------------------------------
3r03 A  2.83186    ------------------------------------------------------------------------------------------------------LWEFPGGKLEPGETPEAALVRELAEELG-------------------------------------------------------------------------------------------------
3gg6 A  3.37419    ---------------------------------------------------------------------------------------------------------LPAGRMEPGETIVEALQREVKEEAG-------------------------------------------------------------------------------------------------


PSI-BLAST run over CullPDB database (4 iterations)    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3bho A  5.65061e-121    -------------------FGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2du3 A  0.0560996    ----------------------------KEILAERSPNLYPRVGFSFGKEHPLF-------ATIQRLREAYLSIGFSEVVNPLIVEDVH------------------------------------------------------------------------------------------------------------------------------------------
3dgt A  0.0685373    -----------------------------------------------------------------------------------------------------TGTSYPGGAGNWGTGEVESMTSSTSNVSLDGNGDLLITPRRDASGNWTSGRIETTRTDFQPPAGGKLRVEARLQMPNVTGDAAAGYWPAFWMLGAPFRGNYQNWPGVG------------------
3mxm A  1.6057    ----------------------------------------------------------------------------------------------------------PGKACSPGASEITGLSKAELEVQGRQ-----------------------------------------------------------------------------------------------
2v8h A  3.8884    -----------------------------------------------------------------------------------------------ILETGSQF----GGVARWGQESHEGMRRLAGTAL---DGAMRDWFTNEC-----------------------------------------------------------------------------------
2fgt A  4.29788    ---------------------------------------------------------------------------------------------------------------------------------------------------WSNQSFEYSSFDHILIPFNETKANKKIYLVSYSKQLILEVSANYRNIMNDLKNRQSNMPAFS------------------
3gg6 A  5.52032    ----------------------------------------------------------------------------------VLAVFLSEQDEVLLIQEAKRECRLPAGRMEPGETIVEALQREVKEEAG-------------------------------------------------------------------------------------------------
3gzi A  6.68818    -------KSRVGRPSGDTQNRDKLILAARNLFIERQVSIREIASYYFGSKEKLFETAMPVLAQLHKARRETRQAALLQTYYSVMSKHPH-FPRLML-----------------------------------------------------------------------------------------------------------------------------------
3id9 A  7.27016    -------------------------------------------------------------CKFNRKRRLYIENIMQVRVTGILIEDEK----VLLVKVANRDWSLPGGRVENGETLEEAMIREMREETG-------------------------------------------------------------------------------------------------
3rg8 A  7.33108    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALVLEPKNAALLAARIFSLYDK-----------------------


PHYRE - remote method    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2cl3 A  2.3e-30    ------HHHSSGVDLGTENFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2pbt D  8.9e-05    ---------------------------------------------------------------------------MKKEFSAGGVLFKDG--EVLLIKTPSNVWSFPKGNIEPGEKPEETAVREVWEETGV------KGEILDYIGE--------IHYWY-TLKGERIFKTVKYYLMKYKEGEPRPSWEVKDAKFFPIKEA--------------------------
1pun A  9.6e-05    ----------------------------------------------------------------------------KLQIAVGIIRNENN--EIFITRRAADKLEFPGGKIEMGETPEQAVVRELQEEVGITPQHFSLFEKLE----YEFPDRHITL---------------WFWLVERWEGE----PWGKEGEWMSLVGL--------------------------
1vcd A1  0.0001    ---------------------------------------------------------------------------MELGAGGVVF---NAKREVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGV------RAEVLLPLYPYVNPKG--------------------------------------------------------------------------
2azw A1  0.00012    ---------------------------------------------------------------------------TRYAAYIIVS--KPENNTMVLVQAPNGAYFLPGGEIEGTETKEEAIHREVLEELGI------SVEIGCYLGEADE-------YFYSNHRQTAYYNPGYFYVANTWRQLSEPLERTNTLHWVAPEEA--------------------------
2fb1 A2  0.00013    -----------------------------------------------------------------------------LGIDCIIFGFNEGEISLLLLKRAMGEWSLMGGFVQKDESVDDAAKRVLAELTGLENVYM------EQVGAFGAIDRD-----------PGERVVSIAYYALININEYDRELVKHNAYWVNINEL--------------------------
2o1c C  0.00015    ----------------------------------------------------------------------------PVSILVVIYAQDTK--RVLMLQRDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEI-FSHLRHRY-APGVTR--NTESWFCLALPHERQIVFTEHLAYKWLDAPAA--------------------------
2fvv A1  0.00016    ----------------------------------------------------------------------YDGDGYKKRAACLCFR-SESEEEVLLVSSSPDRWIVPGGGMEPEEEPSVAAVREVCEEAGV------KGTLGRLVGIFENQERKHRTYVYV------------------------------------------------------------------
2yyh C  0.00019    ----------------------------------------------------------------------------LLATDVIIRLDGENFKGIVLIERPPVGLALPGGFVEVGERVEEAAAREMREETGL------EVRLHKLMGVYSDPERDPRAH---------------------------------------------------------------------
1rya A  0.00021    ----------------------------------------------------------------------------LVSLDFIVE---NSRGEFLLGKRAQGYWFVPGGRVQKDETLEAAFERLTMAELGLPITAGQFYGVWQHFYDDNFSGTDFT-----------THYVVLGFRFRVSEEELLLPDEQHDYRWLTSDAL--------------------------


FFAS - remote method    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3bap A  -119    MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2cl3 A  -115    MSSGVDLGTENLYF---QSMGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3p5t A  -110    ---------------------------------ERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2azw A  -16.7    -------------------------------------------------------------------REETLTYQTRYAAYIIVSKPENNT--MVLVQAPNGAYFLPGGEIEGTETKEEAIHREVLEELG-------SVEIGCYLGE-------ADEYFYSNHRQTAYYNPGYFYVANTWRQLSEPLERTNTLHWVAPEEA-VRLLKRGSHRWAVEKWLAAAS----
2pqv A  -16.6    -------------------------------------------------------------NAMTQQDFRTKVDNTVFGVRATALIVQNH----LLVTKDKGKYYTIGGAIQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEF---------------HYLVDLLEDAPLTMQEDEKRQPCEWIDL-DKLQNIQLVPVFLKTALPDWE----
3f13 A  -15.7    ------------------------------------------------------------------------------RRATAIIEMPDG---VLVTASRGGRYNLPGGKANRGELRSQALIREIREETGL------RINSMLYLFDHITPFNAHKVY--AQGQPKPQNEIERIALVSSPDTDMDLFVEGRAILR--------------------------------
2o1c A  -14.7    ----------------------------------------------------------------------MKDKVYKRPVSILVVIYAQDTKRVLMLQRDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQ---TLIDCQRTVEFEIFSHLRHRYAPGVTRNTES--WFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNR-QAIEQFVINAA----
2fvv A  -14.6    --------------------------------------------------GTENLYFQSMMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKG------TLGRLVGIFENQERKHRTYVYLEDWEDSVNIGRKREWFKIEDAIKV-LQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMS
3mcf A  -14.1    ---------------------------------------------------------------------------MKKRAACLCFRSEREDEVLLVSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKG------KLGRLLGVF--------------EQNQDPEHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLK----
2duk A  -14.1    -------------------------------------------------------------------TRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKG------KLGRLLGIFENQD---------------RKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLG--


mGenThreader    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3bho A  3e-16    -------------------FGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGR-----QDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
2qkm B  0.008    IRAQNDQLPSLG----LRVFSAKLFAHC-----------------------PLLWKWS---KVHEEAFDDFLRYKTRIPVRGAIMLDM-SMQQCVLVKGWSSGWGFPKGKIDKDESDVDCAIREVYEETGCSSRINPNEFIDMTIRGSLDTRFESRT----------RKEISKIEWHNLMDLPTFKKNKPQ-----------TMKNKFYPFLAPLKKWIKKRNIANN
3q1p A  0.014    --------------------------------------------------TITYSKDVYDIERFQQLRDISISMMSHYTVDIRAVVFQNE--KLLFVKEGK--WALPGGWADVGYTPTEVAAKEVFEETG--------YEVDHLLAIFDKEKHQPSPSAT---HKKTSIETEEVEFFGENELPNLSIARNTEDQIKEMFAYMKD-PQKEKLID--------------
1xsa A  0.014    --------------------------------------------------------------------------GMALRACGLIIFRRCLIPEFLLLQASDGHWTPPKGHVEPGEDDLETALRATQEEAGIEAGQNKPKTVIYWLAEVKDYDVE----------IRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSI---EAL----------------
3gwy A  0.016    --------------------------------------------------------------------------SLKSEVVAAVIRLGE---KYLCVQRFR--YEFPGGKVEEGESLQEALQREIMEEMD------YVIEVGEKLLTVHHT------YPDFE-------ITMHAFLCHPVGQRY--VLKEHQWLSTREMAILDWAEADKPIVRKISE----------
3f6a A  0.021    ---------------------------------------------------------------------------LNRTVSVFIVCKD----KVLLHLHKAKKMLPLGGHIEVNELPEEACIREAKEEAGLNDVSPNHSHI-DFVYYATTTSFETSP---------EIGESKILKWYSKEDKNAHNIQENILVMATEALDLLE------------------------
2a6t A  0.021    ILNLPAEEQSSQLPSGLRVFSAKLFAHCPLLWKWHE-----------------------------EAFDDFLRYKTRIPVRGAIMLDM-SMQQCVLVKGASSGWGFPKGKIDKDESDVDCAIREVYEETGFSSRINPNEFIDMTIR----------------------GQNVRLYIIP-------GISLDTNLMDLPTFKMKNKFYMVIPFLAPLKKWIKKRNIANN
2qjo A  0.024    IRGAYFEGKEGDYLDKVPPAIADYLQTFQK-----------------------SERYIALCDEYQFLQAYKQAWATAPYITTDAVVVQAG--HVLMVRRGLGLIALPGGFIKQNETLVEGMLRELKEETRLKVPVLRGSIVDSHVFD-------------APGRSLRGRTITHAYFIQLPGGE---LPAVKKAWWMSLADLYAQEEQIYEIIQHFV-----------
2kdv A  0.025    ---------------------------------------------------------------------------MRPNV-GIVICNRQG--QVMWARRGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDTRNWLRYKLPKRLVRWDTKPVCIAEINMQTSSTPEFDGWRWVSYWYSLQENTPK--------------------------------------
3son A  0.025    -----------------------------------------------------------------------------QQVLVIPFIKTEANYQFGVLHRTDAVWQFVAGGGEDEEAISETAKRESIEELNLDVDV--KMYSLDSHASIPNFHF-SFNKPYCSYQVTLSLEHSELRWVSYESAIQLLEWDSNKTALYELNERLKNNDMKAM-----------------


PCONS5    

    1........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....
pdbid score model   MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3bho A  1.611    -------------------FGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
3gg6 A  0.7881    ---------------------------------------------------------------------------------------------------------LPAGRMEPGETIVEALQREVKEEAG-------------------------------------------------------------------------------------------------
1vcd A  0.7329    ---------------------------------------------------------------------------MELGAGGVVFNAKR---EVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGVRAEV------LLPLYPT--------RYVN--PK---GVEREVHWFLMRGEGAPRLEEGMTGAGWFSPEEARALL-AFPEDLGLLEVALERLPL---
2xsq A  0.6733    --------------------------MHHHHHHSSGVD--------LGTENLY---FQSMAARRLELGEALALSGWRHVCHALLYAGRIPLRYAILMQMFDGRLGFPGGFVDTQDSLEDGLNRELREELGEAAAAF-RVERTDYRSSHVGSG---------------PRVVAHFYAKRLTLEELLAVEAGLGLVRVPLYTLRDGV-------GGLPTFLEN-SFIGS
2fvv A  0.6379    --------------------------MHHHHHHSSGVD--------LGTEN---LYFQSMMKLKSNQTRTYDGDGYKKRAACLCFRSESE-EEVLLVSSSPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKG------TLGRLVGIFENQERK---------------HRTYVYVLIVTEVLE-DWEDGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGATTYS
1ktg A  0.5063    ---------------------------------------------------------------------------MVKAAGLVIYRKLAGKIEFLLLQASYPHWTPPKGHVDPGEDEWQAAIRETKEEANITKE---QLTIHDCHET-LFYEAK---------G---KPKSVKYWLAKLNNPDDVQLSHHQNWKWCELEDAIKIYAEMGSLLRKFSAFLAGF-----
3id9 A  0.4757    --------------------------------------------------------------KFNRKRRLYIENIMQVRVTGILIEDE----KVLLVKVANRDWSLPGGRVENGETLEEAMIREMREETG-------------------------------------------------------------------------------------------------
1u20 A  0.4478    ----------------MAE----------SR-----------------SPD-RGAKEDKPRPRNISREESLQLEGYKHACHALL-HAPSQIRRVLLMMMFDGRLGFPGGFVDTRDSLEEGLKRELEEELGPALAT-VEVTEDDYRSSQVR------EHP--------QKCVTHFYIKELKLEEIERIVEVMGLIRVPLYTLRDR-------VGGLPAFLC-NNFIGN
3gz5 A  0.4264    -----------------------------------------------GSHMTEAE-------YL----ANYDPKAQLLTVDAVLFTYHDQQLKVLLVQRSNGLWGLPGGFIDEDESLEQTVLRKLAEKTAVVPPYI------EQLCTVGNNSRDAVYTALMSYQAIQIASVSDVKWWPLADVLQMPLAFDHQLIEQARERLT-QKALYSLVPGFAPELQHVHEVLLG
3f13 A  0.4174    ---------------------------------------------------------MSLEDRNERLPS-------DLARRATAIIEMPD--GVLVTASRGGRYNLPGGKANRGELRSQALIREIREETGLRIN------SMLYLFDHITPFN--AHKVYLQGQPKPQNEIERIALVS-SPDTDMDLFVEGRAI-LR--RYARLRNEETAKGEALRALLGLARYIAK


b) disorder predictors:
DISOPRED2 result file casp_logo
DISpro result file casp_logo
DISPROT (VSL2) result file casp_logo
GlobPlot result file casp_logo
iPDA result file casp_logo
IUPred long result file casp_logo
IUPred short result file casp_logo
Pdisorder result file casp_logo
Poodle-l result file casp_logo
Poodle-s result file casp_logo
PrDOS result file casp_logo
RONN result file casp_logo
Spritz long result file casp_logo
Spritz short result file casp_logo
DisEMBL coils result file casp_logo
DisEMBL hotloops result file casp_logo
DisEMBL remark465 result file casp_logo