Molecule image

m2,8A

Summary

Full name2,8-dimethyladenosine
Short namem2,8A
New Nomenclature28A
RNAMods abbreviation±
Enzymes Cfr (Staphylococcus sciuri)
Found in phylogenyEubacteria
Found in RNArRNA
SMILESCC1=NC(=C2N=C(C)[N](C3OC(CO)C(O)C3O)C2=N1)N
SMILES (no stereochemical information)CC1=NC(=C2N=C(C)[N](C3OC(CO)C(O)C3O)C2=N1)N

LC-MS Information

Sum formulaC12H17N5O4
Monoisotopic mass295.1281
Average mass295.2983
[M+H]+296.1358
Product ions164
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

3D Molecule representation

Download [.mol file for m2,8A]

Chemical groups contained

TypeSubtype
methyl groupmethyl group

Reactions producing 2,8-dimethyladenosine

Name
m2A:m2,8A
m8A:m2,8A

Publications

Title Authors Journal Details PubMed Id DOI
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria. Giessing AM, Jensen SS, Rasmussen A, Hansen LH, Gondela A, Long K, Vester B, Kirpekar F RNA [details] 19144912 -

Last modification of this entry: Oct. 6, 2017

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