Molecule image

ms2io6A

Summary

Full name2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine
Short namems2io6A
New Nomenclature2160A
RNAMods abbreviation
Enzymes MiaE (Salmonella typhimurium)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILESC/C(CO)=C\CNc3nc(SC)nc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O
SMILES (no stereochemical information)C/C(CO)=C\CNc3nc(SC)nc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O

LC-MS Information

Sum formulaC16O5N5H23S1
Monoisotopic mass397.142
Average mass397.4546
[M+H]+398.1498
Product ions266
Normalized LC elution time *3,19 (Kellner 2014)
LC elution order/characteristicsafter m6A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.


LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

3D Molecule representation

Download [.mol file for ms2io6A]

Chemical groups contained

TypeSubtype
heavy atomthiomethyl
otherhydroxyl
otherisopentenyl

Reactions producing 2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine

Name
io6A:ms2io6A
ms2i6A:ms2io6A

Last modification of this entry: Oct. 6, 2017

Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact: Pietro Boccaletto