Molecule image



Full name5-(isopentenylaminomethyl)-2-thiouridine
Short nameinm5s2U
New Nomenclature2583U
RNAMods abbreviation½
Found in phylogeny
Found in RNA
SMILES (no stereochemical information)CC(C)=CCNCC1=CN(C2OC(CO)C(O)C2O)C(=S)NC1=O

LC-MS Information

Sum formulaC15H23N3O5S
Monoisotopic mass357.1358
Average mass357.4308
Product ions226
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

3D Molecule representation

Download [.mol file for inm5s2U]


5-(isopentenylaminomethyl)uridine and 2-thio-5-(isopentenylaminomethyl)uridine were identified in tRNA of Thermodesulfobacterium commune. Their identities were determined by mass spectrometry and confirmed by chemical synthesis. Data were presented at the tRNA meeting in Banz, Germany (1985) by P.F. Crain, D.R. Phillips, T. Hashizume and F. Widdel. Since then, beside the Banz-meeting abstract, no paper was published about these modified nucleosides.

Reactions producing 5-(isopentenylaminomethyl)-2-thiouridine


Last modification of this entry: Oct. 6, 2017

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