Molecule image
Summary
Full name | 5-carboxymethylaminomethyl-2-geranylthiouridine |
Short name | cmnm5ges2U |
New Nomenclature | 2151U |
RNAMods abbreviation | f |
Enzymes |
MnmH (Escherichia coli)
|
Found in phylogeny | Eubacteria |
Found in RNA | tRNA |
SMILES | O=C(O)CNCC1=CN(C(=NC1=O)SC\C=C(/C)CC\C=C(/C)C)[C@@H]2O[C@H](CO)[C@H](O)C2O |
SMILES (no stereochemical information) | O=C(O)CNCC1=CN(C(=NC1=O)SC\C=C(/C)CC\C=C(/C)C)[C@@H]2O[C@H](CO)[C@H](O)C2O |
LC-MS Information
Sum formula | C22H33N3O7S |
Monoisotopic mass | 483.2039 |
Average mass | 483.586 |
[M+H]+ | 484.2117 |
Product ions | 352 |
Normalized LC elution time * | not available |
LC elution order/characteristics | not available |
* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.
3D Molecule representation
Comments
Present in position 34 in a small fraction of E. coli tRNAGlnUUG.
Chemical groups contained
Type | Subtype |
aminoalkyl | carboxymethylaminomethyl |
sulphur | thio |
hydrocarbon | geranyl |
Reactions producing 5-carboxymethylaminomethyl-2-geranylthiouridine
Reactions starting from 5-carboxymethylaminomethyl-2-geranylthiouridine
Publications
Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
Discovery and biological characterization of geranylated RNA in bacteria. |
Dumelin CE, Chen Y, Leconte AM, Chen YG, Liu DR... |
Nat Chem Biol |
[details]
|
22983156
|
-
|
A gain of function mutation in a protein mediates production of novel modified nucleosides. |
Chen P, Crain PF, Nasvall SJ, Pomerantz SC, Bjork GR... |
EMBO J |
[details]
|
15861125
|
-
|
Last modification of this entry: Oct. 6, 2017