Molecule image
Summary
| Full name | 7-methylguanosine cap (cap 0) |
| Short name | m7Gpp(pN) |
| New Nomenclature | 79553N |
| RNAMods abbreviation | © |
| Enzymes |
Abd1 (Saccharomyces cerevisiae) Hcm1 (Homo sapiens) |
| Found in phylogeny | Eukaryota |
| Found in RNA | mRNA, snRNA |
| SMILES | [O-]P([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@H](n2c[n+](C)c1c2N=C(N)NC1=O)C(O)[C@@H]3O |
| SMILES (no stereochemical information) | [O-]P([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@H](n2c[n+](C)c1c2N=C(N)NC1=O)C(O)[C@@H]3O |
LC-MS Information
| Sum formula | C11H15N5O11P2 |
| Monoisotopic mass | 455.0243 |
| Average mass | 455.2147 |
| [M+H]+ | not available |
| Product ions | not available |
| Normalized LC elution time * | not available |
| LC elution order/characteristics | not available |
* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.
3D Molecule representation
Download [.mol file for m7Gpp(pN)]
Comments
wikipedia: The 5' cap is found on the 5' end of an mRNA molecule and consists of a guanine nucleotide connected to the mRNA via an unusual 5' to 5' triphosphate linkage. This guanosine is methylated on the 7 position directly after capping in vitro by a methyl transferase. It is referred to as a 7-methylguanosine cap, abbreviated m7G. Most properties, save the triphosphate linkage, are the same as any other 7-methylguanosine.
Chemical groups contained
| Type | Subtype |
|---|---|
| methyl group | methyl group |
Reactions producing 7-methylguanosine cap (cap 0)
| Name |
|---|
| Gpp(pN):m7Gpp(pN) |
Reactions starting from 7-methylguanosine cap (cap 0)
| Name |
|---|
| m7Gpp(pN):m2,7Gpp(pN) |
| m7Gpp(pN):m7GpppNm |
| m7Gpp(pN):m7GpppNNm |
Last modification of this entry: Oct. 6, 2017