Modomics - A Database of RNA Modifications

Molecule image

Summary

Full name	N2,7-dimethylguanosine cap (cap DMG)
Short name	m2,7Gpp(pN)
New Nomenclature	279553N
RNAMods abbreviation	®
Enzymes	Tgs1 (Homo sapiens)
Found in phylogeny	Eukaryota
Found in RNA
SMILES	[O-]P([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@H](n2c[n+](C)c1c2N=C(NC)NC1=O)C(O)[C@@H]3O
SMILES (no stereochemical information)	[O-]P([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@H](n2c[n+](C)c1c2N=C(NC)NC1=O)C(O)[C@@H]3O

LC-MS Information

Sum formula	C₁₂H₁₇N₅O₁₁P₂
Monoisotopic mass	469.04
Average mass	469.2416
[M+H]⁺	not available
Product ions	not available
Normalized LC elution time^*	not available
LC elution order/characteristics	not available

^* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

3D Molecule representation

Download [.mol file for m2,7Gpp(pN)]

Comments

As with the m7G cap, the m2,7G cap is indistinguishable from any other m7m2G apart from the triester linkage linking it to the rest of the RNA chain, and I'm putting it here separately just for orderliness purpose.

Chemical groups contained

Type	Subtype
methyl group	methyl at aromatic N

Reactions producing N2,7-dimethylguanosine cap (cap DMG)

Name
m7Gpp(pN):m2,7Gpp(pN)

Reactions starting from N2,7-dimethylguanosine cap (cap DMG)

Name
m2,7Gpp(pN):m2,2,7Gpp(pN)

Last modification of this entry: Oct. 6, 2017