Full name | N6,N6-dimethyladenosine |
Short name | m6,6A |
New Nomenclature | 66A |
RNAMods abbreviation | ζ |
Enzymes |
RsmA (Escherichia coli) RsmA (Saccharomyces cerevisiae) RsmA (Thermus thermophilus) |
Found in phylogeny | Eubacteria, Eukaryota |
Found in RNA | rRNA |
PubChem ID | 72266 |
SMILES | C3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(C)(C) |
SMILES (no stereochemical information) | C3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(C)(C) |
Sum formula | C12O4N5H17 |
Monoisotopic mass | 295.1281 |
Average mass | 295.2989 |
[M+H]+ | 296.1359 |
Product ions | 164 |
Normalized LC elution time * | 1,86 (Kellner 2014); 2,57 (Kellner 2014) |
LC elution order/characteristics | after m6A (Kellner 2014, Kellner 2014) |
* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.
Title | Authors | Journal | Details | ||
---|---|---|---|---|---|
Profiling of RNA modifications by multiplexed stable isotope labelling. | Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. | Chem Commun (Camb). | [details] | 24567952 | - |
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. | Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC... | Nat Protoc | [details] | 24625781 | - |
Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. | Kellner S, Ochel A, Thuring K, Spenkuch F, Neumann J, Sharma S, Entian KD, Schneider D, Helm M... | Nucleic Acids Res | [details] | 25129236 | - |
Download [.mol file for m6,6A]
Type | Subtype |
---|---|
methyl group | methyl at other N |
methyl group | second methyl at other N |
Name |
---|
m6A:m6,6A |
Name |
---|
m6,6A:m6,6Am |
PDB-ID | chain | residue |
---|---|---|
1wts | MA6/8 | |
1wts | MA6/9 | |
1wtt | MA6/8 | |
1wtt | MA6/9 | |
2i1c | y | MA6/1518 |
2i1c | y | MA6/1519 |
Last modification of this entry: Oct. 6, 2017