Molecule image

io6A

Summary

Full nameN6-(cis-hydroxyisopentenyl)adenosine
Short nameio6A
New Nomenclature60A
RNAMods abbreviation`
Enzymes MiaE (Salmonella typhimurium)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILESC3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(CC=C(C)/CO)
SMILES (no stereochemical information)C3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(CC=C(C)/CO)

LC-MS Information

Sum formulaC15O5N5H21
Monoisotopic mass351.1543
Average mass351.3632
[M+H]+352.1621
Product ions220
Normalized LC elution time *2,59 (Kellner 2014)
LC elution order/characteristicsafter m6A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.


LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

3D Molecule representation

Download [.mol file for io6A]

Chemical groups contained

TypeSubtype
otherhydroxyl
otherisopentenyl

Reactions producing N6-(cis-hydroxyisopentenyl)adenosine

Name
i6A:io6A

Reactions starting from N6-(cis-hydroxyisopentenyl)adenosine

Name
io6A:ms2io6A

Last modification of this entry: Oct. 6, 2017

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