Molecule image



Full nameN6-isopentenyladenosine
Short namei6A
New Nomenclature61A
RNAMods abbreviation+
Enzymes MiaA (Escherichia coli)
Mod5 (Saccharomyces cerevisiae)
Mod5 (Homo sapiens)
Found in phylogenyEubacteria, Eukaryota
Found in RNAtRNA
PubChem ID266767
SMILES (no stereochemical information)C3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(CC=C(C)C)

LC-MS Information

Sum formulaC15O4N5H21
Monoisotopic mass335.1594
Average mass335.3639
Product ions204/136/148
Normalized LC elution time *3,24 (Kellner 2014)
LC elution order/characteristicsafter m6A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC... Nat Protoc [details] 24625781 -

3D Molecule representation

Download [.mol file for i6A]

Chemical groups contained


Reactions producing N6-isopentenyladenosine


Reactions starting from N6-isopentenyladenosine


Occurrence in PDB structures

PDB-ID chain residue
1k5e A ABR/6
1k5f A ABS/6

Last modification of this entry: Oct. 6, 2017

Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact: Pietro Boccaletto