Molecule image
Summary
Full name | N6-methyl-N6-threonylcarbamoyladenosine |
Short name | m6t6A |
New Nomenclature | 662A |
RNAMods abbreviation | E |
Enzymes |
TRMO (Homo sapiens)
TrmO (Escherichia coli)
|
Found in phylogeny | Eubacteria |
Found in RNA | tRNA |
SMILES | O=C(O)C(NC(=O)N(C)c3ncnc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O)C(C)O |
SMILES (no stereochemical information) | O=C(O)C(NC(=O)N(C)c3ncnc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O)C(C)O |
LC-MS Information
Sum formula | C16O8N6H22 |
Monoisotopic mass | 426.1499 |
Average mass | 426.3868 |
[M+H]+ | 427.1577 |
Product ions | 295 |
Normalized LC elution time * | 1,93 (Kellner 2014)
|
LC elution order/characteristics | between A and m6A (Kellner 2014) |
* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.
LC-MS Publications
Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
Profiling of RNA modifications by multiplexed stable isotope labelling. |
Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. |
Chem Commun (Camb). |
[details]
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24567952
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3D Molecule representation
Chemical groups contained
Type | Subtype |
aminoacyl group | threonyl |
methyl group | methyl at other N |
other | carbamoyl |
Reactions producing N6-methyl-N6-threonylcarbamoyladenosine
Occurrence in PDB structures
PDB-ID |
chain |
residue |
1qf6 |
B |
AET/37 |
Last modification of this entry: Oct. 6, 2017