Molecule image



Full nameN6-methyl-N6-threonylcarbamoyladenosine
Short namem6t6A
New Nomenclature662A
RNAMods abbreviationE
Enzymes TRMO (Homo sapiens)
TrmO (Escherichia coli)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILES (no stereochemical information)O=C(O)C(NC(=O)N(C)c3ncnc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O)C(C)O

LC-MS Information

Sum formulaC16O8N6H22
Monoisotopic mass426.1499
Average mass426.3868
Product ions295
Normalized LC elution time *1,93 (Kellner 2014)
LC elution order/characteristicsbetween A and m6A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

3D Molecule representation

Download [.mol file for m6t6A]

Chemical groups contained

aminoacyl groupthreonyl
methyl groupmethyl at other N

Reactions producing N6-methyl-N6-threonylcarbamoyladenosine


Occurrence in PDB structures

PDB-ID chain residue
1qf6 B AET/37

Last modification of this entry: Oct. 6, 2017

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