Molecule image

ac4C

Summary

Full nameN4-acetylcytidine
Short nameac4C
New Nomenclature42C
RNAMods abbreviationM
Enzymes NAT10 (Homo sapiens)
Rra1 (Saccharomyces cerevisiae)
TmcA (Escherichia coli)
Found in phylogenyEubacteria, Eukaryota
Found in RNArRNA, tRNA
SMILESC3(OC(CO)C(O)C(O)3)N1C=CC(N(C(=O)C))=NC1(=O)
SMILES (no stereochemical information)C3(OC(CO)C(O)C(O)3)N1C=CC(N(C(=O)C))=NC1(=O)

LC-MS Information

Sum formulaC11O6N3H15
Monoisotopic mass285.0961
Average mass285.257
[M+H]+286.1039
Product ions154/112
Normalized LC elution time *1,35 (Kellner 2014)
LC elution order/characteristicsbetween G and A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.


LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -
Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. Kellner S, Ochel A, Thuring K, Spenkuch F, Neumann J, Sharma S, Entian KD, Schneider D, Helm M... Nucleic Acids Res [details] 25129236 -

3D Molecule representation

Download [.mol file for ac4C]

Chemical groups contained

TypeSubtype
otheracetylamide

Reactions producing N4-acetylcytidine

Name
C:ac4C

Reactions starting from N4-acetylcytidine

Name
ac4C:ac4Cm

Last modification of this entry: Oct. 6, 2017

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