Molecule image

m4Cm

Summary

Full nameN4,2′-O-dimethylcytidine
Short namem4Cm
New Nomenclature04C
RNAMods abbreviationλ
Enzymes RsmI (Escherichia coli)
RsmH (Escherichia coli)
Found in phylogenyEubacteria
Found in RNArRNA
SMILESC3(OC(CO)C(O)C(O(C))3)N1C=CC(N(C))=NC1(=O)
SMILES (no stereochemical information)C3(OC(CO)C(O)C(O(C))3)N1C=CC(N(C))=NC1(=O)

LC-MS Information

Sum formulaC11O5N3H17
Monoisotopic mass271.1168
Average mass271.2737
[M+H]+272.1246
Product ions126
Normalized LC elution time *1,20 (Kellner 2014)
LC elution order/characteristicsbetween G and A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.


LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

3D Molecule representation

Download [.mol file for m4Cm]

Chemical groups contained

TypeSubtype
methyl groupmethyl at O2
methyl groupmethyl at other N

Reactions producing N4,2′-O-dimethylcytidine

Name
m4C:m4Cm
Cm:m4Cm

Reactions starting from N4,2′-O-dimethylcytidine

Name
m4Cm:m4,4Cm

Occurrence in PDB structures

PDB-ID chain residue
2i1c y 4OC/1402

Last modification of this entry: Oct. 6, 2017

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