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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Alterna - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Alterna & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric Alterna Multilign(seed)
MCC 0.702 > 0.668
Average MCC ± 95% Confidence Intervals 0.712 ± 0.388 > 0.628 ± 0.728
Sensitivity 0.685 > 0.629
Positive Predictive Value 0.735 > 0.727
Total TP 61 > 56
Total TN 3201 < 3207
Total FP 23 > 21
Total FP CONTRA 5 < 6
Total FP INCONS 17 > 15
Total FP COMP 1 > 0
Total FN 28 < 33
P-value 0.0

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Performance plots


  1. Comparison of performance of Alterna and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Alterna and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Alterna and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Alterna and Multilign(seed)).

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Performance of Alterna - scored higher in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 61
Total TN 3201
Total FP 23
Total FP CONTRA 5
Total FP INCONS 17
Total FP COMP 1
Total FN 28
Total Scores
MCC 0.702
Average MCC ± 95% Confidence Intervals 0.712 ± 0.388
Sensitivity 0.685
Positive Predictive Value 0.735
Nr of predictions 4

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2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2LC8_A 0.47 0.44 0.53 8 513 7 0 7 0 10
3RKF_A 0.82 0.79 0.86 19 844 3 1 2 0 5
3SD1_A 0.55 0.55 0.57 16 1505 12 4 8 0 13

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 56
Total TN 3207
Total FP 21
Total FP CONTRA 6
Total FP INCONS 15
Total FP COMP 0
Total FN 33
Total Scores
MCC 0.668
Average MCC ± 95% Confidence Intervals 0.628 ± 0.728
Sensitivity 0.629
Positive Predictive Value 0.727
Nr of predictions 4

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.