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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidHomfold‑LAST & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric CentroidHomfold‑LAST RNASampler(seed)
MCC 0.594 > 0.581
Average MCC ± 95% Confidence Intervals 0.557 ± 0.529 > 0.540 ± 0.454
Sensitivity 0.541 > 0.495
Positive Predictive Value 0.663 < 0.692
Total TP 59 > 54
Total TN 7711 < 7722
Total FP 44 > 33
Total FP CONTRA 9 > 4
Total FP INCONS 21 > 20
Total FP COMP 14 > 9
Total FN 50 < 55
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidHomfold-LAST and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidHomfold‑LAST and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidHomfold-LAST and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidHomfold‑LAST and RNASampler(seed)).

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Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 59
Total TN 7711
Total FP 44
Total FP CONTRA 9
Total FP INCONS 21
Total FP COMP 14
Total FN 50
Total Scores
MCC 0.594
Average MCC ± 95% Confidence Intervals 0.557 ± 0.529
Sensitivity 0.541
Positive Predictive Value 0.663
Nr of predictions 5

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
2LC8_A -0.03 0.00 0.00 0 517 11 0 11 0 18
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.77 0.66 0.90 19 1512 2 1 1 0 10
4A1C_2 0.24 0.25 0.24 5 4495 29 8 8 13 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 54
Total TN 7722
Total FP 33
Total FP CONTRA 4
Total FP INCONS 20
Total FP COMP 9
Total FN 55
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.540 ± 0.454
Sensitivity 0.495
Positive Predictive Value 0.692
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.