CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Carnac(seed)
MCC 0.682 > 0.172
Average MCC ± 95% Confidence Intervals 0.653 ± 0.245 > 0.078 ± 0.199
Sensitivity 0.627 > 0.030
Positive Predictive Value 0.750 < 1.000
Total TP 84 > 4
Total TN 10100 < 10208
Total FP 43 > 0
Total FP CONTRA 6 > 0
Total FP INCONS 22 > 0
Total FP COMP 15 > 0
Total FN 50 < 130
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 84
Total TN 10100
Total FP 43
Total FP CONTRA 6
Total FP INCONS 22
Total FP COMP 15
Total FN 50
Total Scores
MCC 0.682
Average MCC ± 95% Confidence Intervals 0.653 ± 0.245
Sensitivity 0.627
Positive Predictive Value 0.750
Nr of predictions 6

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4A1C_3 0.96 0.92 1.00 34 2729 1 0 0 1 3
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 10208
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 130
Total Scores
MCC 0.172
Average MCC ± 95% Confidence Intervals 0.078 ± 0.199
Sensitivity 0.030
Positive Predictive Value 1.000
Nr of predictions 6

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.