CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric ContextFold MXScarna(20)
MCC 0.698 > 0.586
Average MCC ± 95% Confidence Intervals 0.668 ± 0.320 > 0.536 ± 0.323
Sensitivity 0.638 > 0.543
Positive Predictive Value 0.771 > 0.643
Total TP 74 > 63
Total TN 9588 > 9586
Total FP 37 < 62
Total FP CONTRA 6 < 10
Total FP INCONS 16 < 25
Total FP COMP 15 < 27
Total FN 42 < 53
P-value 0.0

^top




Performance plots


  1. Comparison of performance of ContextFold and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and MXScarna(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and MXScarna(20)).

^top





Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 74
Total TN 9588
Total FP 37
Total FP CONTRA 6
Total FP INCONS 16
Total FP COMP 15
Total FN 42
Total Scores
MCC 0.698
Average MCC ± 95% Confidence Intervals 0.668 ± 0.320
Sensitivity 0.638
Positive Predictive Value 0.771
Nr of predictions 5

^top



2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4A1C_3 0.96 0.92 1.00 34 2729 1 0 0 1 3
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top



Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 63
Total TN 9586
Total FP 62
Total FP CONTRA 10
Total FP INCONS 25
Total FP COMP 27
Total FN 53
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.536 ± 0.323
Sensitivity 0.543
Positive Predictive Value 0.643
Nr of predictions 5

^top



2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4A1C_3 0.80 0.78 0.83 29 2728 12 0 6 6 8
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.