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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Mastr(seed)
MCC 0.732 > 0.000
Average MCC ± 95% Confidence Intervals 0.719 ± 0.194 > 0.000 ± 0.000
Sensitivity 0.673 > 0.000
Positive Predictive Value 0.804 > 0.000
Total TP 115 > 0
Total TN 12521 < 12664
Total FP 50 > 0
Total FP CONTRA 6 > 0
Total FP INCONS 22 > 0
Total FP COMP 22 > 0
Total FN 56 < 171
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Mastr(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 115
Total TN 12521
Total FP 50
Total FP CONTRA 6
Total FP INCONS 22
Total FP COMP 22
Total FN 56
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.719 ± 0.194
Sensitivity 0.673
Positive Predictive Value 0.804
Nr of predictions 8

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
3J16_L 0.90 0.81 1.00 17 1142 0 0 0 0 4
3UZL_B 0.93 0.88 1.00 14 1279 7 0 0 7 2
4A1C_3 0.96 0.92 1.00 34 2729 1 0 0 1 3
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 12664
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 171
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 8

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 528 0 0 0 0 18
3J16_L 0.00 0.00 0.00 0 1159 0 0 0 0 21
3UZL_B 0.00 0.00 0.00 0 1293 0 0 0 0 16
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.