CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MCFold - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MCFold & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric MCFold Multilign(seed)
MCC 0.669 > 0.668
Average MCC ± 95% Confidence Intervals 0.690 ± 0.475 > 0.628 ± 0.728
Sensitivity 0.674 > 0.629
Positive Predictive Value 0.682 < 0.727
Total TP 60 > 56
Total TN 3196 < 3207
Total FP 31 > 21
Total FP CONTRA 1 < 6
Total FP INCONS 27 > 15
Total FP COMP 3 > 0
Total FN 29 < 33
P-value 0.0

^top




Performance plots


  1. Comparison of performance of MCFold and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MCFold and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MCFold and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MCFold and Multilign(seed)).

^top





Performance of MCFold - scored higher in this pairwise comparison

1. Total counts & total scores for MCFold

Total Base Pair Counts
Total TP 60
Total TN 3196
Total FP 31
Total FP CONTRA 1
Total FP INCONS 27
Total FP COMP 3
Total FN 29
Total Scores
MCC 0.669
Average MCC ± 95% Confidence Intervals 0.690 ± 0.475
Sensitivity 0.674
Positive Predictive Value 0.682
Nr of predictions 4

^top



2. Individual counts for MCFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2LC8_A 0.44 0.44 0.47 8 511 10 0 9 1 10
3RKF_A 0.89 0.88 0.91 21 843 3 0 2 1 3
3SD1_A 0.43 0.45 0.43 13 1503 17 1 16 0 16

^top



Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 56
Total TN 3207
Total FP 21
Total FP CONTRA 6
Total FP INCONS 15
Total FP COMP 0
Total FN 33
Total Scores
MCC 0.668
Average MCC ± 95% Confidence Intervals 0.628 ± 0.728
Sensitivity 0.629
Positive Predictive Value 0.727
Nr of predictions 4

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.