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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric MXScarna(20) RNASLOpt
MCC 0.586 > 0.560
Average MCC ± 95% Confidence Intervals 0.536 ± 0.323 < 0.598 ± 0.334
Sensitivity 0.543 = 0.543
Positive Predictive Value 0.643 > 0.589
Total TP 63 = 63
Total TN 9586 > 9577
Total FP 62 > 54
Total FP CONTRA 10 < 17
Total FP INCONS 25 < 27
Total FP COMP 27 > 10
Total FN 53 = 53
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 63
Total TN 9586
Total FP 62
Total FP CONTRA 10
Total FP INCONS 25
Total FP COMP 27
Total FN 53
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.536 ± 0.323
Sensitivity 0.543
Positive Predictive Value 0.643
Nr of predictions 5

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4A1C_3 0.80 0.78 0.83 29 2728 12 0 6 6 8
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.