CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Mastr(20) Carnac(seed)
MCC 0.634 > 0.231
Average MCC ± 95% Confidence Intervals 0.570 ± 0.157 > 0.095 ± 0.137
Sensitivity 0.495 > 0.054
Positive Predictive Value 0.819 < 1.000
Total TP 258 > 28
Total TN 43895 < 44182
Total FP 106 > 1
Total FP CONTRA 10 > 0
Total FP INCONS 47 > 0
Total FP COMP 49 > 1
Total FN 263 < 493
P-value 5.1503931209e-08

^top




Performance plots


  1. Comparison of performance of Mastr(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Mastr(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and Carnac(seed)).

^top





Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 258
Total TN 43895
Total FP 106
Total FP CONTRA 10
Total FP INCONS 47
Total FP COMP 49
Total FN 263
Total Scores
MCC 0.634
Average MCC ± 95% Confidence Intervals 0.570 ± 0.157
Sensitivity 0.495
Positive Predictive Value 0.819
Nr of predictions 21

^top



2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 1.00 1.00 1.00 10 164 0 0 0 0 0
2L94_A 0.88 0.83 0.94 15 341 2 0 1 1 3
2XKV_B 0.60 0.36 1.00 4 1831 3 0 0 3 7
2XXA_G 0.44 0.20 1.00 7 2038 0 0 0 0 28
3GX2_A 0.46 0.39 0.55 11 1429 10 2 7 1 17
3IVN_B 0.86 0.83 0.90 19 882 2 2 0 0 4
3IZF_C 0.91 0.91 0.91 32 2605 9 0 3 6 3
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.77 0.80 0.75 12 2362 26 0 4 22 3
3LA5_A 0.89 0.80 1.00 20 934 0 0 0 0 5
3NPB_A 0.34 0.30 0.41 11 2251 18 1 15 2 26
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3O58_2 0.93 0.94 0.94 29 2723 12 0 2 10 2
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

^top



Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 28
Total TN 44182
Total FP 1
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 1
Total FN 493
Total Scores
MCC 0.231
Average MCC ± 95% Confidence Intervals 0.095 ± 0.137
Sensitivity 0.054
Positive Predictive Value 1.000
Nr of predictions 21

^top



2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 1.00 1.00 1.00 10 164 0 0 0 0 0
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2XKV_B 0.00 0.00 0.00 0 1835 0 0 0 0 11
2XXA_G 0.00 0.00 0.00 0 2045 0 0 0 0 35
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3IZF_C 0.00 0.00 0.00 0 2640 0 0 0 0 35
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.00 0.00 0.00 0 2378 0 0 0 0 15
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3O58_2 0.00 0.00 0.00 0 2754 0 0 0 0 31
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.