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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Mastr(20) RNASLOpt
MCC 0.581 > 0.560
Average MCC ± 95% Confidence Intervals 0.461 ± 0.392 < 0.598 ± 0.334
Sensitivity 0.431 < 0.543
Positive Predictive Value 0.794 > 0.589
Total TP 50 < 63
Total TN 9621 > 9577
Total FP 17 < 54
Total FP CONTRA 1 < 17
Total FP INCONS 12 < 27
Total FP COMP 4 < 10
Total FN 66 > 53
P-value 0.0

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Performance plots


  1. Comparison of performance of Mastr(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and RNASLOpt).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 50
Total TN 9621
Total FP 17
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 4
Total FN 66
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.461 ± 0.392
Sensitivity 0.431
Positive Predictive Value 0.794
Nr of predictions 5

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.