CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Multilign(20) RNASLOpt
MCC 0.583 > 0.560
Average MCC ± 95% Confidence Intervals 0.556 ± 0.333 < 0.598 ± 0.334
Sensitivity 0.578 > 0.543
Positive Predictive Value 0.598 > 0.589
Total TP 67 > 63
Total TN 9572 < 9577
Total FP 56 > 54
Total FP CONTRA 13 < 17
Total FP INCONS 32 > 27
Total FP COMP 11 > 10
Total FN 49 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and RNASLOpt).

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Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 67
Total TN 9572
Total FP 56
Total FP CONTRA 13
Total FP INCONS 32
Total FP COMP 11
Total FN 49
Total Scores
MCC 0.583
Average MCC ± 95% Confidence Intervals 0.556 ± 0.333
Sensitivity 0.578
Positive Predictive Value 0.598
Nr of predictions 5

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.88 0.86 0.89 32 2727 6 0 4 2 5
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15
4AOB_A 0.59 0.55 0.64 16 1412 10 3 6 1 13
4ENB_A 0.39 0.33 0.50 5 462 6 0 5 1 10
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.