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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric NanoFolder Mastr(seed)
MCC 0.412 > 0.000
Average MCC ± 95% Confidence Intervals 0.427 ± 0.199 > 0.000 ± 0.000
Sensitivity 0.506 > 0.000
Positive Predictive Value 0.350 > 0.000
Total TP 79 > 0
Total TN 11966 < 12192
Total FP 169 > 0
Total FP CONTRA 52 > 0
Total FP INCONS 95 > 0
Total FP COMP 22 > 0
Total FN 77 < 156
P-value 0.0

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Performance plots


  1. Comparison of performance of NanoFolder and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and Mastr(seed)).

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Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 79
Total TN 11966
Total FP 169
Total FP CONTRA 52
Total FP INCONS 95
Total FP COMP 22
Total FN 77
Total Scores
MCC 0.412
Average MCC ± 95% Confidence Intervals 0.427 ± 0.199
Sensitivity 0.506
Positive Predictive Value 0.350
Nr of predictions 7

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3J16_L 0.43 0.52 0.37 11 1129 19 8 11 0 10
3UZL_B 0.41 0.56 0.31 9 1264 25 10 10 5 7
4A1C_3 0.58 0.68 0.51 25 2714 24 9 15 0 12
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 12192
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 156
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 7

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 528 0 0 0 0 18
3J16_L 0.00 0.00 0.00 0 1159 0 0 0 0 21
3UZL_B 0.00 0.00 0.00 0 1293 0 0 0 0 16
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.