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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Afold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Afold
MCC 0.404 > 0.398
Average MCC ± 95% Confidence Intervals 0.464 ± 2.762 < 0.502 ± 3.969
Sensitivity 0.371 < 0.457
Positive Predictive Value 0.448 > 0.356
Total TP 13 < 16
Total TN 4959 > 4943
Total FP 26 < 46
Total FP CONTRA 2 < 11
Total FP INCONS 14 < 18
Total FP COMP 10 < 17
Total FN 22 > 19
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 13
Total TN 4959
Total FP 26
Total FP CONTRA 2
Total FP INCONS 14
Total FP COMP 10
Total FN 22
Total Scores
MCC 0.404
Average MCC ± 95% Confidence Intervals 0.464 ± 2.762
Sensitivity 0.371
Positive Predictive Value 0.448
Nr of predictions 2

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 16
Total TN 4943
Total FP 46
Total FP CONTRA 11
Total FP INCONS 18
Total FP COMP 17
Total FN 19
Total Scores
MCC 0.398
Average MCC ± 95% Confidence Intervals 0.502 ± 3.969
Sensitivity 0.457
Positive Predictive Value 0.356
Nr of predictions 2

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.19 0.25 0.15 5 4483 43 11 17 15 15
4ENB_A 0.81 0.73 0.92 11 460 3 0 1 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.