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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) CRWrnafold
MCC 0.747 > 0.663
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 < 0.690 ± 0.356
Sensitivity 0.707 > 0.672
Positive Predictive Value 0.796 > 0.661
Total TP 82 > 78
Total TN 9581 > 9566
Total FP 34 < 63
Total FP CONTRA 2 < 12
Total FP INCONS 19 < 28
Total FP COMP 13 < 23
Total FN 34 < 38
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CRWrnafold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 78
Total TN 9566
Total FP 63
Total FP CONTRA 12
Total FP INCONS 28
Total FP COMP 23
Total FN 38
Total Scores
MCC 0.663
Average MCC ± 95% Confidence Intervals 0.690 ± 0.356
Sensitivity 0.672
Positive Predictive Value 0.661
Nr of predictions 5

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.