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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Contrafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Contrafold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Contrafold
MCC 0.747 > 0.624
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.650 ± 0.348
Sensitivity 0.707 > 0.621
Positive Predictive Value 0.796 > 0.637
Total TP 82 > 72
Total TN 9581 > 9571
Total FP 34 < 58
Total FP CONTRA 2 < 12
Total FP INCONS 19 < 29
Total FP COMP 13 < 17
Total FN 34 < 44
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Contrafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Contrafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Contrafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Contrafold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of Contrafold - scored lower in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 72
Total TN 9571
Total FP 58
Total FP CONTRA 12
Total FP INCONS 29
Total FP COMP 17
Total FN 44
Total Scores
MCC 0.624
Average MCC ± 95% Confidence Intervals 0.650 ± 0.348
Sensitivity 0.621
Positive Predictive Value 0.637
Nr of predictions 5

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.21 0.25 0.19 5 4489 33 9 13 11 15
4A1C_3 0.81 0.81 0.81 30 2726 10 0 7 3 7
4AOB_A 0.53 0.52 0.56 15 1410 13 3 9 1 14
4ENB_A 0.85 0.73 1.00 11 461 1 0 0 1 4
4ENC_A 0.85 0.73 1.00 11 485 1 0 0 1 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.