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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of MaxExpect - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & MaxExpect [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) MaxExpect
MCC 0.747 > 0.579
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.567 ± 0.360
Sensitivity 0.707 > 0.586
Positive Predictive Value 0.796 > 0.581
Total TP 82 > 68
Total TN 9581 > 9567
Total FP 34 < 67
Total FP CONTRA 2 < 14
Total FP INCONS 19 < 35
Total FP COMP 13 < 18
Total FN 34 < 48
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and MaxExpect. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and MaxExpect).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and MaxExpect. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and MaxExpect).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of MaxExpect - scored lower in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 68
Total TN 9567
Total FP 67
Total FP CONTRA 14
Total FP INCONS 35
Total FP COMP 18
Total FN 48
Total Scores
MCC 0.579
Average MCC ± 95% Confidence Intervals 0.567 ± 0.360
Sensitivity 0.586
Positive Predictive Value 0.581
Nr of predictions 5

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.19 0.25 0.16 5 4484 41 10 17 14 15
4A1C_3 0.83 0.81 0.86 30 2728 7 0 5 2 7
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.36 0.33 0.42 5 484 8 0 7 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.