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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & PPfold(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) PPfold(20)
MCC 0.747 > 0.732
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.669 ± 0.324
Sensitivity 0.707 > 0.672
Positive Predictive Value 0.796 < 0.804
Total TP 82 > 78
Total TN 9581 < 9587
Total FP 34 > 25
Total FP CONTRA 2 > 1
Total FP INCONS 19 > 18
Total FP COMP 13 > 6
Total FN 34 < 38
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PPfold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PPfold(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of PPfold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 78
Total TN 9587
Total FP 25
Total FP CONTRA 1
Total FP INCONS 18
Total FP COMP 6
Total FN 38
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.669 ± 0.324
Sensitivity 0.672
Positive Predictive Value 0.804
Nr of predictions 5

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15
4A1C_3 0.93 0.92 0.94 34 2727 2 0 2 0 3
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.63 0.47 0.88 7 464 1 0 1 0 8
4ENC_A 0.64 0.53 0.80 8 486 2 0 2 0 7

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.