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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of PknotsRG - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & PknotsRG [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) PknotsRG
MCC 0.747 > 0.672
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 < 0.719 ± 0.421
Sensitivity 0.707 < 0.716
Positive Predictive Value 0.796 > 0.638
Total TP 82 < 83
Total TN 9581 > 9554
Total FP 34 < 63
Total FP CONTRA 2 < 16
Total FP INCONS 19 < 31
Total FP COMP 13 < 16
Total FN 34 > 33
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and PknotsRG. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PknotsRG).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and PknotsRG. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PknotsRG).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of PknotsRG - scored lower in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 83
Total TN 9554
Total FP 63
Total FP CONTRA 16
Total FP INCONS 31
Total FP COMP 16
Total FN 33
Total Scores
MCC 0.672
Average MCC ± 95% Confidence Intervals 0.719 ± 0.421
Sensitivity 0.716
Positive Predictive Value 0.638
Nr of predictions 5

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.18 0.25 0.14 5 4480 43 11 20 12 15
4A1C_3 0.85 0.84 0.86 31 2727 8 0 5 3 6
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.