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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RNAfold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RNAfold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RNAfold
MCC 0.747 > 0.591
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.578 ± 0.372
Sensitivity 0.707 > 0.603
Positive Predictive Value 0.796 > 0.588
Total TP 82 > 70
Total TN 9581 > 9565
Total FP 34 < 70
Total FP CONTRA 2 < 15
Total FP INCONS 19 < 34
Total FP COMP 13 < 21
Total FN 34 < 46
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RNAfold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAfold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RNAfold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAfold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of RNAfold - scored lower in this pairwise comparison

1. Total counts & total scores for RNAfold

Total Base Pair Counts
Total TP 70
Total TN 9565
Total FP 70
Total FP CONTRA 15
Total FP INCONS 34
Total FP COMP 21
Total FN 46
Total Scores
MCC 0.591
Average MCC ± 95% Confidence Intervals 0.578 ± 0.372
Sensitivity 0.603
Positive Predictive Value 0.588
Nr of predictions 5

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2. Individual counts for RNAfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.19 0.25 0.15 5 4482 43 11 18 14 15
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.37 0.33 0.45 5 485 7 0 6 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.