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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RSpredict(20)
MCC 0.747 > 0.428
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.443 ± 0.186
Sensitivity 0.707 > 0.362
Positive Predictive Value 0.796 > 0.519
Total TP 82 > 42
Total TN 9581 < 9603
Total FP 34 < 48
Total FP CONTRA 2 < 13
Total FP INCONS 19 < 26
Total FP COMP 13 > 9
Total FN 34 < 74
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 42
Total TN 9603
Total FP 48
Total FP CONTRA 13
Total FP INCONS 26
Total FP COMP 9
Total FN 74
Total Scores
MCC 0.428
Average MCC ± 95% Confidence Intervals 0.443 ± 0.186
Sensitivity 0.362
Positive Predictive Value 0.519
Nr of predictions 5

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.60 0.49 0.75 18 2739 8 0 6 2 19
4A1C_2 0.25 0.30 0.21 6 4487 30 12 11 7 14
4AOB_A 0.33 0.21 0.55 6 1426 5 1 4 0 23
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.51 0.40 0.67 6 487 3 0 3 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.