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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RSpredict(seed)
MCC 0.747 > 0.219
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.216 ± 0.252
Sensitivity 0.707 > 0.103
Positive Predictive Value 0.796 > 0.480
Total TP 82 > 12
Total TN 9581 < 9659
Total FP 34 > 14
Total FP CONTRA 2 < 4
Total FP INCONS 19 > 9
Total FP COMP 13 > 1
Total FN 34 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 12
Total TN 9659
Total FP 14
Total FP CONTRA 4
Total FP INCONS 9
Total FP COMP 1
Total FN 104
Total Scores
MCC 0.219
Average MCC ± 95% Confidence Intervals 0.216 ± 0.252
Sensitivity 0.103
Positive Predictive Value 0.480
Nr of predictions 5

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.00 0.00 0.00 0 2759 4 2 2 0 37
4A1C_2 0.00 0.00 0.00 0 4512 5 2 2 1 20
4AOB_A 0.42 0.21 0.86 6 1430 1 0 1 0 23
4ENB_A 0.34 0.20 0.60 3 467 2 0 2 0 12
4ENC_A 0.34 0.20 0.60 3 491 2 0 2 0 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.