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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Vsfold4
MCC 0.747 > 0.472
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357 > 0.555 ± 0.307
Sensitivity 0.707 > 0.457
Positive Predictive Value 0.796 > 0.500
Total TP 82 > 53
Total TN 9581 > 9578
Total FP 34 < 67
Total FP CONTRA 2 < 11
Total FP INCONS 19 < 42
Total FP COMP 13 < 14
Total FN 34 < 63
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Vsfold4).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Vsfold4).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 82
Total TN 9581
Total FP 34
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 13
Total FN 34
Total Scores
MCC 0.747
Average MCC ± 95% Confidence Intervals 0.683 ± 0.357
Sensitivity 0.707
Positive Predictive Value 0.796
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.25 0.25 0.25 5 4496 25 2 13 10 15
4A1C_3 1.00 1.00 1.00 37 2726 1 0 0 1 0
4AOB_A 0.87 0.83 0.92 24 1411 4 0 2 2 5
4ENB_A 0.68 0.53 0.89 8 463 1 0 1 0 7
4ENC_A 0.61 0.53 0.73 8 485 3 0 3 0 7

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 53
Total TN 9578
Total FP 67
Total FP CONTRA 11
Total FP INCONS 42
Total FP COMP 14
Total FN 63
Total Scores
MCC 0.472
Average MCC ± 95% Confidence Intervals 0.555 ± 0.307
Sensitivity 0.457
Positive Predictive Value 0.500
Nr of predictions 5

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.36 0.40 0.33 8 4492 28 4 12 12 12
4A1C_3 0.29 0.30 0.31 11 2727 26 4 21 1 26
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.77 0.60 1.00 9 487 0 0 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.