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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Cylofold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Cylofold
MCC 0.773 > 0.694
Average MCC ± 95% Confidence Intervals 0.737 ± 0.238 > 0.728 ± 0.275
Sensitivity 0.702 > 0.675
Positive Predictive Value 0.860 > 0.726
Total TP 80 > 77
Total TN 5292 > 5279
Total FP 28 < 37
Total FP CONTRA 2 < 9
Total FP INCONS 11 < 20
Total FP COMP 15 > 8
Total FN 34 < 37
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Cylofold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 80
Total TN 5292
Total FP 28
Total FP CONTRA 2
Total FP INCONS 11
Total FP COMP 15
Total FN 34
Total Scores
MCC 0.773
Average MCC ± 95% Confidence Intervals 0.737 ± 0.238
Sensitivity 0.702
Positive Predictive Value 0.860
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
3J16_L 1.00 1.00 1.00 21 1138 1 0 0 1 0
3UZL_B 0.93 0.88 1.00 14 1279 8 0 0 8 2
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 77
Total TN 5279
Total FP 37
Total FP CONTRA 9
Total FP INCONS 20
Total FP COMP 8
Total FN 37
Total Scores
MCC 0.694
Average MCC ± 95% Confidence Intervals 0.728 ± 0.275
Sensitivity 0.675
Positive Predictive Value 0.726
Nr of predictions 6

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
3J16_L 0.90 0.81 1.00 17 1142 0 0 0 0 4
3UZL_B 0.45 0.50 0.42 8 1274 18 4 7 7 8
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.