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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of MCFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & MCFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) MCFold
MCC 0.808 > 0.546
Average MCC ± 95% Confidence Intervals 0.738 ± 0.247 > 0.524 ± 0.274
Sensitivity 0.754 > 0.579
Positive Predictive Value 0.872 > 0.525
Total TP 95 > 73
Total TN 9825 > 9795
Total FP 30 < 91
Total FP CONTRA 3 < 16
Total FP INCONS 11 < 50
Total FP COMP 16 < 25
Total FN 31 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and MCFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and MCFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 95
Total TN 9825
Total FP 30
Total FP CONTRA 3
Total FP INCONS 11
Total FP COMP 16
Total FN 31
Total Scores
MCC 0.808
Average MCC ± 95% Confidence Intervals 0.738 ± 0.247
Sensitivity 0.754
Positive Predictive Value 0.872
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
3J16_L 1.00 1.00 1.00 21 1138 1 0 0 1 0
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4A1C_3 1.00 1.00 1.00 37 2726 2 0 0 2 0
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of MCFold - scored lower in this pairwise comparison

1. Total counts & total scores for MCFold

Total Base Pair Counts
Total TP 73
Total TN 9795
Total FP 91
Total FP CONTRA 16
Total FP INCONS 50
Total FP COMP 25
Total FN 53
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.524 ± 0.274
Sensitivity 0.579
Positive Predictive Value 0.525
Nr of predictions 6

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2. Individual counts for MCFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.44 0.44 0.47 8 511 10 0 9 1 10
3J16_L 0.54 0.57 0.52 12 1136 12 4 7 1 9
4A1C_2 0.18 0.25 0.14 5 4480 45 12 19 14 15
4A1C_3 0.86 0.86 0.86 32 2726 9 0 5 4 5
4ENB_A 0.78 0.73 0.85 11 459 4 0 2 2 4
4ENC_A 0.34 0.33 0.38 5 483 11 0 8 3 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.