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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) RDfolder
MCC 0.745 > 0.317
Average MCC ± 95% Confidence Intervals 0.698 ± 0.285 > 0.320 ± 0.267
Sensitivity 0.673 > 0.286
Positive Predictive Value 0.835 > 0.384
Total TP 66 > 28
Total TN 4013 < 4019
Total FP 20 < 46
Total FP CONTRA 2 < 6
Total FP INCONS 11 < 39
Total FP COMP 7 > 1
Total FN 32 < 70
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RDfolder).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 66
Total TN 4013
Total FP 20
Total FP CONTRA 2
Total FP INCONS 11
Total FP COMP 7
Total FN 32
Total Scores
MCC 0.745
Average MCC ± 95% Confidence Intervals 0.698 ± 0.285
Sensitivity 0.673
Positive Predictive Value 0.835
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
3J16_L 1.00 1.00 1.00 21 1138 1 0 0 1 0
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 28
Total TN 4019
Total FP 46
Total FP CONTRA 6
Total FP INCONS 39
Total FP COMP 1
Total FN 70
Total Scores
MCC 0.317
Average MCC ± 95% Confidence Intervals 0.320 ± 0.267
Sensitivity 0.286
Positive Predictive Value 0.384
Nr of predictions 5

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 514 14 3 11 0 18
3J16_L 0.26 0.24 0.31 5 1143 11 0 11 0 16
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 0.48 0.40 0.60 6 462 4 0 4 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 0 4 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.