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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of RNAalifold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & RNAalifold(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) RNAalifold(20)
MCC 0.835 > 0.656
Average MCC ± 95% Confidence Intervals 0.773 ± 0.205 > 0.620 ± 0.344
Sensitivity 0.784 > 0.578
Positive Predictive Value 0.892 > 0.753
Total TP 91 > 67
Total TN 9582 < 9595
Total FP 28 > 26
Total FP CONTRA 3 < 5
Total FP INCONS 8 < 17
Total FP COMP 17 > 4
Total FN 25 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and RNAalifold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RNAalifold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and RNAalifold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RNAalifold(20)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 91
Total TN 9582
Total FP 28
Total FP CONTRA 3
Total FP INCONS 8
Total FP COMP 17
Total FN 25
Total Scores
MCC 0.835
Average MCC ± 95% Confidence Intervals 0.773 ± 0.205
Sensitivity 0.784
Positive Predictive Value 0.892
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4A1C_3 1.00 1.00 1.00 37 2726 2 0 0 2 0
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of RNAalifold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 67
Total TN 9595
Total FP 26
Total FP CONTRA 5
Total FP INCONS 17
Total FP COMP 4
Total FN 49
Total Scores
MCC 0.656
Average MCC ± 95% Confidence Intervals 0.620 ± 0.344
Sensitivity 0.578
Positive Predictive Value 0.753
Nr of predictions 5

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15
4A1C_3 0.90 0.84 0.97 31 2731 1 0 1 0 6
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.