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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) TurboFold(seed)
MCC 0.786 > 0.552
Average MCC ± 95% Confidence Intervals 0.713 ± 0.219 > 0.532 ± 0.378
Sensitivity 0.724 > 0.530
Positive Predictive Value 0.858 > 0.587
Total TP 97 > 71
Total TN 10099 > 10091
Total FP 33 < 65
Total FP CONTRA 3 < 15
Total FP INCONS 13 < 35
Total FP COMP 17 > 15
Total FN 37 < 63
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and TurboFold(seed)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 97
Total TN 10099
Total FP 33
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 17
Total FN 37
Total Scores
MCC 0.786
Average MCC ± 95% Confidence Intervals 0.713 ± 0.219
Sensitivity 0.724
Positive Predictive Value 0.858
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4A1C_3 1.00 1.00 1.00 37 2726 2 0 0 2 0
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 71
Total TN 10091
Total FP 65
Total FP CONTRA 15
Total FP INCONS 35
Total FP COMP 15
Total FN 63
Total Scores
MCC 0.552
Average MCC ± 95% Confidence Intervals 0.532 ± 0.378
Sensitivity 0.530
Positive Predictive Value 0.587
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.