CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt Carnac(seed)
MCC 0.551 > 0.172
Average MCC ± 95% Confidence Intervals 0.579 ± 0.257 > 0.078 ± 0.199
Sensitivity 0.522 > 0.030
Positive Predictive Value 0.593 < 1.000
Total TP 70 > 4
Total TN 10094 < 10208
Total FP 58 > 0
Total FP CONTRA 17 > 0
Total FP INCONS 31 > 0
Total FP COMP 10 > 0
Total FN 64 < 130
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 70
Total TN 10094
Total FP 58
Total FP CONTRA 17
Total FP INCONS 31
Total FP COMP 10
Total FN 64
Total Scores
MCC 0.551
Average MCC ± 95% Confidence Intervals 0.579 ± 0.257
Sensitivity 0.522
Positive Predictive Value 0.593
Nr of predictions 6

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 10208
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 130
Total Scores
MCC 0.172
Average MCC ± 95% Confidence Intervals 0.078 ± 0.199
Sensitivity 0.030
Positive Predictive Value 1.000
Nr of predictions 6

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.