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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(20) Multilign(seed)
MCC 0.829 > 0.795
Average MCC ± 95% Confidence Intervals 0.840 ± 0.173 > 0.818 ± 0.233
Sensitivity 0.740 < 0.750
Positive Predictive Value 0.937 > 0.852
Total TP 74 < 75
Total TN 4114 > 4105
Total FP 7 < 14
Total FP CONTRA 0 < 5
Total FP INCONS 5 < 8
Total FP COMP 2 > 1
Total FN 26 > 25
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and Multilign(seed)).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 74
Total TN 4114
Total FP 7
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 2
Total FN 26
Total Scores
MCC 0.829
Average MCC ± 95% Confidence Intervals 0.840 ± 0.173
Sensitivity 0.740
Positive Predictive Value 0.937
Nr of predictions 4

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.81 0.69 0.95 20 1512 1 0 1 0 9
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 75
Total TN 4105
Total FP 14
Total FP CONTRA 5
Total FP INCONS 8
Total FP COMP 1
Total FN 25
Total Scores
MCC 0.795
Average MCC ± 95% Confidence Intervals 0.818 ± 0.233
Sensitivity 0.750
Positive Predictive Value 0.852
Nr of predictions 4

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.