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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & NanoFolder [.zip] - may take several seconds...


Overview

Metric RNASampler(20) NanoFolder
MCC 0.689 > 0.389
Average MCC ± 95% Confidence Intervals 0.673 ± 0.479 > 0.405 ± 0.473
Sensitivity 0.624 > 0.475
Positive Predictive Value 0.768 > 0.331
Total TP 63 > 48
Total TN 9130 > 9067
Total FP 34 < 114
Total FP CONTRA 3 < 33
Total FP INCONS 16 < 64
Total FP COMP 15 < 17
Total FN 38 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and NanoFolder).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 63
Total TN 9130
Total FP 34
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 15
Total FN 38
Total Scores
MCC 0.689
Average MCC ± 95% Confidence Intervals 0.673 ± 0.479
Sensitivity 0.624
Positive Predictive Value 0.768
Nr of predictions 4

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.24 0.25 0.24 5 4495 30 3 13 14 15
4A1C_3 0.90 0.81 1.00 30 2733 0 0 0 0 7
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 48
Total TN 9067
Total FP 114
Total FP CONTRA 33
Total FP INCONS 64
Total FP COMP 17
Total FN 53
Total Scores
MCC 0.389
Average MCC ± 95% Confidence Intervals 0.405 ± 0.473
Sensitivity 0.475
Positive Predictive Value 0.331
Nr of predictions 4

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4A1C_3 0.58 0.68 0.51 25 2714 24 9 15 0 12
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.